Acoustic impedance measurement of tissue mimicking materials by using scanning acoustic microscopy.

Acoustic impedance Blood Mimicking Fluid (BMF) Scanning acoustic microscopy Soft tissue Tissue-Mimicking Material (TMM)

Journal

Ultrasonics
ISSN: 1874-9968
Titre abrégé: Ultrasonics
Pays: Netherlands
ID NLM: 0050452

Informations de publication

Date de publication:
Feb 2021
Historique:
received: 03 05 2020
revised: 02 10 2020
accepted: 06 10 2020
pubmed: 2 11 2020
medline: 5 1 2021
entrez: 1 11 2020
Statut: ppublish

Résumé

Tissue-mimicking materials (TMMs) play a key role in the quality assurance of ultrasound diagnostic equipment and should have acoustic properties similar to human tissues. We propose a method to quantify the acoustic properties of TMM samples through the use of an 80 MHz Scanning Acoustic Microscopy (SAM), which provides micrometer resolution and fast data recording. We produced breast TMM samples in varying compositions that resulted in acoustic impedance values in the range of 1.373 ± 0.031 and 1.707 ± 0.036 MRayl. Additionally, liver TMM and blood mimicking fluid (BMF) samples were prepared that had acoustic impedance values of 1.693 ± 0.085 MRayl and 1.624 ± 0.006 MRayl, respectively. The characterization of the TMMs by SAM may provide reproducible and uniform acoustic reference data for tissue substitutes in a single-run microscopy experiment.

Identifiants

pubmed: 33130362
pii: S0041-624X(20)30212-2
doi: 10.1016/j.ultras.2020.106274
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

106274

Informations de copyright

Copyright © 2020 Elsevier B.V. All rights reserved.

Auteurs

Burak Altun (B)

Bogazici University, Institute of Biomedical Engineering, Istanbul 34684, Turkey.

Irem Demirkan (I)

Bogazici University, Department of Physics, Istanbul 34342, Turkey.

Esin Ozturk Isik (EO)

Bogazici University, Institute of Biomedical Engineering, Istanbul 34684, Turkey.

Ozgur Kocaturk (O)

Bogazici University, Institute of Biomedical Engineering, Istanbul 34684, Turkey.

Mehmet Burcin Unlu (MB)

Bogazici University, Department of Physics, Istanbul 34342, Turkey; Global Station for Quantum Medical Science and Engineering, Global Institution for Collaborative Research and Education (GI-CoRE), Hokkaido University, Sapporo 060- 8648, Japan.

Bora Garipcan (B)

Bogazici University, Institute of Biomedical Engineering, Istanbul 34684, Turkey. Electronic address: bora.garipcan@boun.edu.tr.

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Classifications MeSH