SRY-Positive 46, XX Testicular Disorder of Sexual Development With Leydig Cell Tumor.
46
Leydig cell tumor
SRY
XX testicular DSD
Journal
American journal of men's health
ISSN: 1557-9891
Titre abrégé: Am J Mens Health
Pays: United States
ID NLM: 101287723
Informations de publication
Date de publication:
Historique:
entrez:
2
11
2020
pubmed:
3
11
2020
medline:
2
10
2021
Statut:
ppublish
Résumé
The risk of a gonadal tumor is high in testicular disorder of sexual development (DSD) with the Y chromosome, but cases of DSD without the Y chromosome are extremely rare. We reported a gonadal tumor in a phenotypically male individual with 46, XX testicular DSD. A testicular tumor was incidentally found in a 32-year-old phenotypic male who was presented to the hospital with male infertility. A diagnosis of 46, XX testicular DSD was made by the presentation of karyotype analysis of 46, XX with the sex-determining region of the Y chromosome (SRY) positive and gonadal tissue without female gonads. Surgery was performed due to a gradually growing tumor. The partial orchidectomy was performed with the diagnosis of a benign Leydig cell tumor in frozen biopsy.
Identifiants
pubmed: 33131361
doi: 10.1177/1557988320970071
pmc: PMC7607790
doi:
Substances chimiques
SRY protein, human
0
Sex-Determining Region Y Protein
0
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
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