Radiotherapy and Late Effects.

Cancer Survivors Child Child Development Humans Incidence Neoplasms / radiotherapy Radiation Injuries / mortality Radiotherapy / adverse effects
Late effects Pediatric cancer Radiobiology Radiotherapy

Journal

Pediatric clinics of North America
ISSN: 1557-8240
Titre abrégé: Pediatr Clin North Am
Pays: United States
ID NLM: 0401126

Informations de publication

Date de publication:
12 2020
Historique:
entrez: 2 11 2020
pubmed: 3 11 2020
medline: 12 1 2021
Statut: ppublish

Résumé

Advances in multimodality care for patients with pediatric cancer continues to improve long-term survival. The use of surgery, chemotherapy, and radiotherapy may lead to debilitating late effects in childhood cancer survivors. It is critically important to understand, mitigate, and screen for late effects to improve the quality of life in childhood cancer survivors. This review summarizes the use of radiotherapy in children, radiobiology of tissue injury, impact of age on late effects, important organ systems affected by radiotherapy during survivorship, and screening for radiotherapy late effects.

Identifiants

DOI: 10.1016/j.pcl.2020.08.001 PMID: 33131534
pubmed: 33131534
pii: S0031-3955(20)30109-7
doi: 10.1016/j.pcl.2020.08.001
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

1051-1067

Informations de copyright

Copyright © 2020 Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Disclosure J.D. Palmer declares grant funding from Varian Medical Systems and speaking fees from Depuy Synthes (outside the submitted work).

Auteurs

Joshua D Palmer (JD)

Department of Radiation Oncology, The James Cancer Hospital at the Ohio State University Wexner Medical Center, Nationwide Children's Hospital, Columbus, OH, USA.

Matthew D Hall (MD)

Department of Radiation Oncology, Miami Cancer Institute and Nicklaus Children's Hospital, Miami, FL, USA.

Anita Mahajan (A)

Department of Radiation Oncology, The Mayo Clinic, Rochester, MN, USA.

Arnold C Paulino (AC)

Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

Suzanne Wolden (S)

Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

Louis S Constine (LS)

Department of Radiation Oncology, University of Rochester, Rochester, NY, USA; Department of Pediatrics, University of Rochester, Rochester, NY, USA; Department of Radiation Oncology, The Judy DiMarzo Cancer Survivorship Program, James P. Wilmot Cancer Institute, University of Rochester Medical Center, PO Box 647, Rochester, NY 14642, USA. Electronic address: Louis_Constine@urmc.rochester.edu.

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Classifications MeSH

questionsmedicales.fr › Personnes › Survivants › Survivants du cancer › Radiotherapy and Late Effects.
questionsmedicales.fr › Personnes › Tranches d'âge › Enfant › Radiotherapy and Late Effects.
questionsmedicales.fr › Phénomènes physiologiques › Croissance et développement › Développement humain › Développement de l'enfant › Radiotherapy and Late Effects.
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Radiotherapy and Late Effects.
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Collecte de données › Registre civil › Morbidité › Incidence › Radiotherapy and Late Effects.
questionsmedicales.fr › Tumeurs › Radiotherapy and Late Effects.
questionsmedicales.fr › Environnement et santé publique › Santé publique › Hygiène radiologique › Effets des rayonnements › Lésions radiques › Radiotherapy and Late Effects.
questionsmedicales.fr › Thérapeutique › Radiothérapie › Radiotherapy and Late Effects.