Molecular mechanism of CaCC

Amino Acid Substitution Anoctamin-1 / antagonists & inhibitors Binding Sites HEK293 Cells Humans Molecular Docking Simulation Mutagenesis, Site-Directed Mutation, Missense Neoplasm Proteins / antagonists & inhibitors Thiophenes / chemistry
CaCC(inh)-A01 CaCCs Inhibitor Ion channel TMEM16A

Journal

Archives of biochemistry and biophysics
ISSN: 1096-0384
Titre abrégé: Arch Biochem Biophys
Pays: United States
ID NLM: 0372430

Informations de publication

Date de publication:
30 11 2020
Historique:
received: 02 09 2020
revised: 05 10 2020
accepted: 20 10 2020
pubmed: 3 11 2020
medline: 15 12 2020
entrez: 2 11 2020
Statut: ppublish

Résumé

TMEM16A is a calcium-activated chloride channel that is associate with several diseases, including pulmonary diseases, hypertension, diarrhea and cancer. The CaCC

Identifiants

DOI: 10.1016/j.abb.2020.108650 PMID: 33132191
pubmed: 33132191
pii: S0003-9861(20)30659-7
doi: 10.1016/j.abb.2020.108650
pii:
doi:

Substances chimiques

6-t-butyl-2-(furan-2-carboxamido)-4,5,6,7-tetrahydrobenzo(b)thiophene-3-carboxylic acid 0
ANO1 protein, human 0
Anoctamin-1 0
Neoplasm Proteins 0
Thiophenes 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

108650

Informations de copyright

Copyright © 2020 Elsevier Inc. All rights reserved.

Auteurs

Sai Shi (S)

State Key Laboratory of Reliability and Intelligence of Electrical Equipment, Hebei University of Technology, Tianjin, 300401, China; Key Laboratory of Electromagnetic Field and Electrical Apparatus Reliability of Hebei Province, Hebei University of Technology, Tianjin, 300401, China; Key Laboratory of Molecular Biophysics of Hebei Province, Institute of Biophysics, School of Science, Hebei University of Technology, Tianjin, 300401, China.

Shuai Guo (S)

State Key Laboratory of Reliability and Intelligence of Electrical Equipment, Hebei University of Technology, Tianjin, 300401, China; Key Laboratory of Electromagnetic Field and Electrical Apparatus Reliability of Hebei Province, Hebei University of Technology, Tianjin, 300401, China; Key Laboratory of Molecular Biophysics of Hebei Province, Institute of Biophysics, School of Science, Hebei University of Technology, Tianjin, 300401, China; College of Life Science, Hebei University, Baoding, 071002, Hebei, China.

Yafei Chen (Y)

Key Laboratory of Molecular Biophysics of Hebei Province, Institute of Biophysics, School of Science, Hebei University of Technology, Tianjin, 300401, China.

Fude Sun (F)

Key Laboratory of Molecular Biophysics of Hebei Province, Institute of Biophysics, School of Science, Hebei University of Technology, Tianjin, 300401, China.

Chunli Pang (C)

Key Laboratory of Molecular Biophysics of Hebei Province, Institute of Biophysics, School of Science, Hebei University of Technology, Tianjin, 300401, China.

Biao Ma (B)

State Key Laboratory of Reliability and Intelligence of Electrical Equipment, Hebei University of Technology, Tianjin, 300401, China; Key Laboratory of Electromagnetic Field and Electrical Apparatus Reliability of Hebei Province, Hebei University of Technology, Tianjin, 300401, China; Key Laboratory of Molecular Biophysics of Hebei Province, Institute of Biophysics, School of Science, Hebei University of Technology, Tianjin, 300401, China.

Chang Qu (C)

State Key Laboratory of Reliability and Intelligence of Electrical Equipment, Hebei University of Technology, Tianjin, 300401, China; Key Laboratory of Electromagnetic Field and Electrical Apparatus Reliability of Hebei Province, Hebei University of Technology, Tianjin, 300401, China; Key Laboratory of Molecular Biophysics of Hebei Province, Institute of Biophysics, School of Science, Hebei University of Technology, Tianjin, 300401, China.

Hailong An (H)

State Key Laboratory of Reliability and Intelligence of Electrical Equipment, Hebei University of Technology, Tianjin, 300401, China; Key Laboratory of Electromagnetic Field and Electrical Apparatus Reliability of Hebei Province, Hebei University of Technology, Tianjin, 300401, China; Key Laboratory of Molecular Biophysics of Hebei Province, Institute of Biophysics, School of Science, Hebei University of Technology, Tianjin, 300401, China. Electronic address: hailong_an@hebut.edu.cn.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female

Evaluation of Low-Value Services Across Major Medicare Advantage Insurers and Traditional Medicare.

Ciara Duggan, Adam L Beckman, Ishani Ganguli et al.
1.00
Humans United States Aged Cross-Sectional Studies Medicare Part C

Effectiveness of Virtual Yoga for Chronic Low Back Pain: A Randomized Clinical Trial.

Hallie Tankha, Devyn Gaskins, Amanda Shallcross et al.
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH

questionsmedicales.fr › Phénomènes génétiques › Mutagenèse › Substitution d'acide aminé › Molecular mechanism of CaCC
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Protéines de transport membranaire › Canaux ioniques › Canaux chlorure › Anoctamines › Anoctamine-1 › Molecular mechanism of CaCC
questionsmedicales.fr › Phénomènes chimiques › Phénomènes biochimiques › Sites de fixation › Molecular mechanism of CaCC
questionsmedicales.fr › Cellules › Cellules épithéliales › Cellules HEK293 › Molecular mechanism of CaCC
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Molecular mechanism of CaCC
questionsmedicales.fr › Sciences de l'information › Méthodologies informatiques › Simulation numérique › Simulation de docking moléculaire › Molecular mechanism of CaCC
questionsmedicales.fr › Techniques d'investigation › Techniques génétiques › Génie génétique › Ingénierie des protéines › Mutagenèse dirigée › Molecular mechanism of CaCC
questionsmedicales.fr › Phénomènes génétiques › Variation génétique › Mutation › Mutation faux-sens › Molecular mechanism of CaCC
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines tumorales › Molecular mechanism of CaCC
questionsmedicales.fr › Composés hétérocycliques › Composés hétéromonocycliques › Thiophènes › Molecular mechanism of CaCC