Anti-feline immunodeficiency virus reverse transcriptase properties of some medicinal and edible mushrooms.
crude extracts
feline immunodeficiency virus
fluorescence spectroscopy
mushrooms
reverse transcriptase
Journal
Veterinary world
ISSN: 0972-8988
Titre abrégé: Vet World
Pays: India
ID NLM: 101504872
Informations de publication
Date de publication:
Sep 2020
Sep 2020
Historique:
received:
19
03
2020
accepted:
06
07
2020
entrez:
2
11
2020
pubmed:
3
11
2020
medline:
3
11
2020
Statut:
ppublish
Résumé
Feline immunodeficiency virus (FIV) causes AIDS-like symptoms in domestic and wild cats. Treatment of infected cats has been performed using human anti-HIV drugs, which showed some limitations. This study aimed to determine the anti-FIV potential of some mushrooms. A total of 17 medicinal and edible mushrooms were screened to find their inhibitory effect against FIV reverse transcriptase (FIV-RT). Three solvents, water, ethanol, and hexane, were used to prepare crude mushroom extracts. Fluorescence spectroscopy was used to perform relative inhibition and 50% inhibitory concentrations (IC The ethanol extract from dried fruiting bodies of The extracts from
Sections du résumé
BACKGROUND AND AIM
OBJECTIVE
Feline immunodeficiency virus (FIV) causes AIDS-like symptoms in domestic and wild cats. Treatment of infected cats has been performed using human anti-HIV drugs, which showed some limitations. This study aimed to determine the anti-FIV potential of some mushrooms.
MATERIALS AND METHODS
METHODS
A total of 17 medicinal and edible mushrooms were screened to find their inhibitory effect against FIV reverse transcriptase (FIV-RT). Three solvents, water, ethanol, and hexane, were used to prepare crude mushroom extracts. Fluorescence spectroscopy was used to perform relative inhibition and 50% inhibitory concentrations (IC
RESULTS
RESULTS
The ethanol extract from dried fruiting bodies of
CONCLUSION
CONCLUSIONS
The extracts from
Identifiants
pubmed: 33132590
doi: 10.14202/vetworld.2020.1798-1806
pii: Vetworld-13-1798
pmc: PMC7566271
doi:
Types de publication
Journal Article
Langues
eng
Pagination
1798-1806Informations de copyright
Copyright: © Seetaha, et al.
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