Antidepressant Use in Siblings of Children With Cancer: A Danish Population-Based Cohort Study.
Journal
JNCI cancer spectrum
ISSN: 2515-5091
Titre abrégé: JNCI Cancer Spectr
Pays: England
ID NLM: 101721827
Informations de publication
Date de publication:
Oct 2020
Oct 2020
Historique:
received:
27
09
2019
revised:
15
05
2020
accepted:
08
06
2020
entrez:
2
11
2020
pubmed:
3
11
2020
medline:
3
11
2020
Statut:
epublish
Résumé
Siblings of children with cancer experience severe stress early in life. Most studies of mental health problems in these siblings are limited by being small, cross-sectional, or self-reporting. In a population-based cohort study, we investigated the risk for antidepressant use by linking several nationwide, population-based registries comparing 6644 siblings of children diagnosed with cancer from 1991-2009 with 128 436 population-based sibling comparisons using the Cox proportional hazards model. Irrespective of cancer type, no increased risk of antidepressant use in siblings of children with cancer was found (hazard ratio = 1.00, 95% confidence interval = 0.91 to 1.11). However, data suggested that siblings being young at cancer diagnosis had an increased risk (2-sided
Identifiants
pubmed: 33134828
doi: 10.1093/jncics/pkaa046
pii: pkaa046
pmc: PMC7583159
doi:
Types de publication
Journal Article
Langues
eng
Pagination
pkaa046Informations de copyright
© The Author(s) 2020. Published by Oxford University Press.
Références
Neurosci Biobehav Rev. 2008 Aug;32(6):1073-86
pubmed: 18423592
Lancet Oncol. 2013 Sep;14(10):971-80
pubmed: 23954078
Scand J Public Health. 2011 Jul;39(7 Suppl):42-5
pubmed: 21775350
Psychooncology. 2011 Dec;20(12):1259-68
pubmed: 22114043
Scand J Public Health. 2011 Jul;39(7 Suppl):12-6
pubmed: 21898916
Int J Cancer. 1987 Nov 15;40(5):620-4
pubmed: 3679589
Eur J Cancer. 2015 Mar;51(5):675-84
pubmed: 25677304
Scand J Public Health. 2011 Jul;39(7 Suppl):38-41
pubmed: 21775349
Dan Med Bull. 2006 Nov;53(4):441-9
pubmed: 17150149