Unilateral Isolated Primary Cutaneous Amyloidosis of the External Auditory Canal.


Journal

The journal of international advanced otology
ISSN: 2148-3817
Titre abrégé: J Int Adv Otol
Pays: Turkey
ID NLM: 101522982

Informations de publication

Date de publication:
Dec 2020
Historique:
entrez: 2 11 2020
pubmed: 3 11 2020
medline: 23 9 2021
Statut: ppublish

Résumé

Isolated primary cutaneous amyloidosis (PCA) of the external ear is extremely rare. We describe the case of a 65-year-old woman presenting with itching within the left external auditory canal (EAC). Otoscopy revealed a 3 mm whitish lesion involving the cartilaginous portion of the left EAC. The lesion was excised. Histological and immunohistochemical features were consistent with keratinic amyloidosis. A clinical workup was negative for systemic amyloidosis. As far as we know, only nine cases of PCA exclusively involving the EAC have been reported. The frequent occurrence of itching in these patients and the keratinic nature of the amyloid support the role of chronic stimulation/irritation in the pathogenesis of isolated amyloidosis the EAC.

Identifiants

pubmed: 33136030
doi: 10.5152/iao.2020.7570
pmc: PMC7901453
doi:

Types de publication

Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

467-469

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Auteurs

Giuseppe Magliulo (G)

Department of Sense Organs, Sapienza University of Rome, Rome, Italy.

Ludovica de Vincentiis (L)

Department of Molecular Medicine, Sapienza University of Rome, Italy.

Annalisa Pace (A)

Department of Sense Organs, Sapienza University of Rome, Rome, Italy.

Irene Claudia Visconti (IC)

Department of Sense Organs, Sapienza University of Rome, Rome, Italy.

Francesco Le Foche (F)

Department of Public Health and Infectious Diseases, Sapienza University of Rome, Italy.

Mara Riminucci (M)

Department of Molecular Medicine, Sapienza University of Rome, Italy.

Alessandro Corsi (A)

Department of Molecular Medicine, Sapienza University of Rome, Italy.

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Classifications MeSH