Adapting Index/Partner Services for the Treatment of Chlamydia Among Young African American Men in a Community Screening Program.
Journal
Sexually transmitted diseases
ISSN: 1537-4521
Titre abrégé: Sex Transm Dis
Pays: United States
ID NLM: 7705941
Informations de publication
Date de publication:
01 05 2021
01 05 2021
Historique:
pubmed:
3
11
2020
medline:
25
5
2021
entrez:
2
11
2020
Statut:
ppublish
Résumé
Screening for asymptomatic Chlamydia trachomatis (Ct) among men has not been recommended because feasibility and efficacy are unknown. Check It is a seek-test-treat community-based Ct screening program for African American men who have sex with women and who are 15 to 24 years of age. This is an evaluation of adaptations made to the program aimed at improving index/partner notification and treatment rates. The original Check It intervention included free testing and treatment, contact tracing performed by a third party, expedited index therapy, and expedited partner therapy via pharmacy pickup. The intervention was adapted after a series of in-depth interviews eliciting information to refine the program. Changes included continuity of testing, notification, and treatment by the same staff; expanded hours; and patient-delivered partner therapy with a medication mail-delivery option. Rates of index male and partner treatment were compared using log-binomial models and generalized estimating equations. Men in the adapted intervention (n = 85) were more likely than men in the original intervention (n = 99) to be contacted (relative risk [RR], 1.14; 95% confidence interval [CI], 1.02-1.27), make a treatment plan (RR, 1.14; 95% CI, 1.01-1.27), and complete treatment (RR, 1.45; 95% CI, 1.20-1.75). Female sexual partners were significantly more likely to complete treatment in postadaptation (n = 153) compared with preadaptation (n = 161; RR, 3.02; 95% CI, 1.81-5.05). Compared with third-party notification and expedited index therapy/expedited partner therapy available by pharmacy pickup only, patient-delivered partner therapy with mail-delivery option, staff available at nontraditional hours, and staff continuity across testing, notification, and treatment significantly improved index and partner treatment completion.
Sections du résumé
BACKGROUND
Screening for asymptomatic Chlamydia trachomatis (Ct) among men has not been recommended because feasibility and efficacy are unknown. Check It is a seek-test-treat community-based Ct screening program for African American men who have sex with women and who are 15 to 24 years of age. This is an evaluation of adaptations made to the program aimed at improving index/partner notification and treatment rates.
METHODS
The original Check It intervention included free testing and treatment, contact tracing performed by a third party, expedited index therapy, and expedited partner therapy via pharmacy pickup. The intervention was adapted after a series of in-depth interviews eliciting information to refine the program. Changes included continuity of testing, notification, and treatment by the same staff; expanded hours; and patient-delivered partner therapy with a medication mail-delivery option. Rates of index male and partner treatment were compared using log-binomial models and generalized estimating equations.
RESULTS
Men in the adapted intervention (n = 85) were more likely than men in the original intervention (n = 99) to be contacted (relative risk [RR], 1.14; 95% confidence interval [CI], 1.02-1.27), make a treatment plan (RR, 1.14; 95% CI, 1.01-1.27), and complete treatment (RR, 1.45; 95% CI, 1.20-1.75). Female sexual partners were significantly more likely to complete treatment in postadaptation (n = 153) compared with preadaptation (n = 161; RR, 3.02; 95% CI, 1.81-5.05).
CONCLUSIONS
Compared with third-party notification and expedited index therapy/expedited partner therapy available by pharmacy pickup only, patient-delivered partner therapy with mail-delivery option, staff available at nontraditional hours, and staff continuity across testing, notification, and treatment significantly improved index and partner treatment completion.
Identifiants
pubmed: 33137012
pii: 00007435-202105000-00004
doi: 10.1097/OLQ.0000000000001325
pmc: PMC8043978
mid: NIHMS1640289
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
323-328Subventions
Organisme : NICHD NIH HHS
ID : R01 HD086794
Pays : United States
Organisme : NCATS NIH HHS
ID : TL1 TR001418
Pays : United States
Informations de copyright
Copyright © 2020 American Sexually Transmitted Diseases Association. All rights reserved.
Déclaration de conflit d'intérêts
Conflict of Interest and Sources of Funding: None declared.
Références
Braxton J, Davis D, Emergson B, Flagg E. Sexually Transmitted Disease Surveillance 2017 [Internet] 2017. US Department of Health and Human Services Centers for Disease Control and Prevention. Available at: https://www.cdc.gov/std/stats17/2017-STD-Surveillance-Report_CDC-clearance-9.10.18.pdf . Accessed June 7, 2020.
Hillis SD, Wasserheit JN. Screening for chlamydia: A key to the prevention of pelvic inflammatory disease. N Engl J Med 1996; 334:1399–1401.
Cohen MS. Sexually transmitted diseases enhance HIV transmission: No longer a hypothesis. Lancet 1998; 351:S5–S7.
Ward H, Rönn M. Contribution of sexually transmitted infections to the sexual transmission of HIV. Curr Opin HIV AIDS 2010; 5:305–310.
Owusu-Edusei K Jr., Chesson HW, Gift TL, et al. The estimated direct medical cost of selected sexually transmitted infections in the United States, 2008. Sex Transm Dis 2013; 40:197–201.
Torrone E, Papp J, Weinstock H; Centers for Disease Control and Prevention (CDC). Prevalence of Chlamydia trachomatis genital infection among persons aged 14–39 years—United States, 2007–2012. MMWR Morb Mortal Wkly Rep 2014; 63:834–838.
Kissinger P, Schmidt N, Mohammed H, et al. Patient-delivered partner treatment for Trichomonas vaginalis infection: A randomized controlled trial. Sex Transm Dis 2006; 33:445–450.
National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention. Annual report 2012 [Internet]. 2012. Available at: https://www.cdc.gov/nchhstp/publications/docs/nchhstp-annualreport-2012-508.pdf . Accessed June 5, 2020.
Mase WA, Hansen AR, Smallwood SW, et al. Disease intervention specialist education for the future: An analysis of public health curricula. Public Health Rep 2018; 133:738–748.
Centers for Disease Control and Prevention. Expedited partner therapy in the management of sexually transmitted diseases [Internet]. 2006. Available at: http://www.cdc.gov/std/treatment/eptfinalreport2006.pdf . Accessed June 7, 2020.
Trelle S, Shang A, Nartey L, et al. Improved effectiveness of partner notification for patients with sexually transmitted infections: Systematic review. BMJ 2007; 334:354.
Centers for Disease Control and Prevention. Legal status of expedited partner therapy (EPT) [Internet]. Sex Transm Dis 2020. Available at: https://www.cdc.gov/std/ept/legal/default.htm . Accessed May 31, 2020.
Althaus CL, Turner KM, Mercer CH, et al. Effectiveness and cost-effectiveness of traditional and new partner notification technologies for curable sexually transmitted infections: Observational study, systematic reviews and mathematical modelling. Health Technol Assess 2014; 18:1–100.
Kissinger PJ, Schmidt N, Gomes G, et al. Contact tracing vs patient-delivered partner treatment for African American heterosexual men with chlamydia. Sex Transm Infect 2019; 96(Suppl 1):A67.
Chandler R, Gordon MS, Kruszka B, et al. Cohort profile: Seek, test, treat and retain United States criminal justice cohort. Subst Abuse Treat Prev Policy 2017; 12:24.
Jurstrand M, Christerson L, Klint M, et al. Characterisation of Chlamydia trachomatis by ompA sequencing and multilocus sequence typing in a Swedish county before and after identification of the new variant. Sex Transm Infect 2010; 86:56–60.
McNutt LA, Wu C, Xue X, et al. Estimating the relative risk in cohort studies and clinical trials of common outcomes. Am J Epidemiol 2003; 157:940–943.
Liang KY, Zeger SL. Longitudinal data analysis using generalized linear models. Biometrika 1986; 73:13–22.
Harris PA, Taylor R, Thielke R, et al. Research electronic data capture (REDCap)—a metadata-driven methodology and workflow process for providing translational research informatics support. J Biomed Inform 2009; 42:377–381. Available at: http://dx.doi.org/10.1016/j.jbi.2008.08.010 .
doi: 10.1016/j.jbi.2008.08.010
Kerr JC, Valois RF, Diclemente RJ, et al. HIV-related stigma among African-American youth in the northeast and southeast US. AIDS Behav 2014; 18:1063–1067.
Kissinger P, Mohammed H, Richardson-alston G, et al. Patient-delivered partner treatment for male urethritis: A randomized, controlled trial. Clin Infect Dis 2005; 41:623–629.
Adams AS, Uratsu C, Dyer W, et al. Health system factors and antihypertensive adherence in a racially and ethnically diverse cohort of new users. JAMA Intern Med 2013; 173:54–61.
Zhang L, Zakharyan A, Stockl KM, et al. Mail-order pharmacy use and medication adherence among Medicare part D beneficiaries with diabetes. J Med Econ 2011; 14:562–567.
Centers for Disease Control and Prevention (CDC). Recommendations for partner services programs for HIV infection, syphilis, gonorrhea, and chlamydial infection. MMWR Recomm Rep 2008; 57(RR-9):1–83.
Workowski KA, Bolan GA; Centers for Disease Control and Prevention. Sexually transmitted diseases treatment guidelines, 2015. MMWR Recomm Rep 2015; 64:1–137.
Hart GJ, Duncan B, Fenton KA. Chlamydia screening and sexual health. Sex Transm Infect 2002; 78:396–397.
Gopalappa C, Huang YL, Gift TL, et al. Cost-effectiveness of screening men in Maricopa county jails for chlamydia and gonorrhea to avert infections in women. Sex Transm Dis 2013; 40:776–783.
Montgomery KA, Gonzalez EW, Montgomery OC. Self-disclosure of sexually transmitted diseases. Holist Nurs Pract 2008; 22:268–279.
Gursahaney PR, Jeong K, Dixon BW, et al. Partner notification of sexually transmitted diseases: Practices and preferences. Sex Transm Dis 2011; 38:821–827.