Non-Alcoholic Steatohepatitis as a Risk Factor for Intrahepatic Cholangiocarcinoma and Its Prognostic Role.

intrahepatic cholangiocarcinoma liver cirrhosis non-alcoholic fatty liver disease non-alcoholic steatohepatitis outcome

Journal

Cancers
ISSN: 2072-6694
Titre abrégé: Cancers (Basel)
Pays: Switzerland
ID NLM: 101526829

Informations de publication

Date de publication:
29 Oct 2020
Historique:
received: 07 09 2020
revised: 21 10 2020
accepted: 27 10 2020
entrez: 3 11 2020
pubmed: 4 11 2020
medline: 4 11 2020
Statut: epublish

Résumé

Non-alcoholic fatty liver disease (NAFLD) and its most aggressive form, non-alcoholic steatohepatitis (NASH), are causing a rise in the prevalence of hepatocellular carcinoma. Data about NAFLD/NASH and intrahepatic cholangiocarcinoma (iCCA) are few and contradictory, coming from population registries that do not correctly distinguish between NAFLD and NASH. We evaluated the prevalence of NAFLD and NASH in peritumoral tissue of resected iCCA (

Identifiants

pubmed: 33138044
pii: cancers12113182
doi: 10.3390/cancers12113182
pmc: PMC7692633
pii:
doi:

Types de publication

Journal Article

Langues

eng

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Auteurs

Stefania De Lorenzo (S)

Oncologia Medica, Azienda Ospedaliero-Universitaria di Bologna, via Albertoni 15, 40138 Bologna, Italy.

Francesco Tovoli (F)

Division of Internal Medicine, Azienda Ospedaliero-Universitaria di Bologna, via Albertoni 15, 40138 Bologna, Italy.

Alessandro Mazzotta (A)

Service de Chirurgie Hépatobiliaire et Digestive, Centre Hospitalier Universitaire Pontchaillou Rennes, CIC-INSERM, Université de Rennes, 35000 Rennes, France.

Francesco Vasuri (F)

Pathology Unit, S. Orsola-Malpighi Bologna Authority Hospital, 40138 Bologna, Italy.

Julien Edeline (J)

Department of Medical Oncology, Centre Eugène Marquis, 35000 Rennes, France.

Deborah Malvi (D)

Pathology Unit, S. Orsola-Malpighi Bologna Authority Hospital, 40138 Bologna, Italy.

Karim Boudjema (K)

Service de Chirurgie Hépatobiliaire et Digestive, Centre Hospitalier Universitaire Pontchaillou Rennes, CIC-INSERM, Université de Rennes, 35000 Rennes, France.

Matteo Renzulli (M)

Radiology Unit, S. Orsola-Malpighi Bologna Authority Hospital, 40138 Bologna, Italy.

Heithem Jeddou (H)

Service de Chirurgie Hépatobiliaire et Digestive, Centre Hospitalier Universitaire Pontchaillou Rennes, CIC-INSERM, Université de Rennes, 35000 Rennes, France.

Antonietta D'Errico (A)

Pathology Unit, S. Orsola-Malpighi Bologna Authority Hospital, 40138 Bologna, Italy.

Bruno Turlin (B)

Service de Pathologie-Centre Hospitalier Universitaire Pontchaillou Rennes, INSERM Numecan U1241, Université de Rennes, Centre de Ressources Biologiques-BB-0033-00056, 35000 Rennes, France.

Matteo Cescon (M)

Surgery Unit, Department of Medical and Surgical Sciences, University of Bologna, 40138 Bologna, Italy.

Thomas Uguen (T)

Service de Hepatologie, Centre Hospitalier Universitaire Pontchaillou, 35000 Rennes, France.

Alessandro Granito (A)

Division of Internal Medicine, Azienda Ospedaliero-Universitaria di Bologna, via Albertoni 15, 40138 Bologna, Italy.

Astrid Lièvre (A)

Department of Gastroenterology, Centre Hospitalier Universitaire Pontchaillou, University of Rennes, Inserm U1242, Rennes, France.

Giovanni Brandi (G)

Oncologia Medica, Azienda Ospedaliero-Universitaria di Bologna, via Albertoni 15, 40138 Bologna, Italy.

Classifications MeSH