In regards to Chu et al.: Patterns of brain metastasis immediately before prophylactic cranial irradiation (PCI): implications for PCI optimization in limited-stage small cell lung cancer.


Journal

Radiation oncology (London, England)
ISSN: 1748-717X
Titre abrégé: Radiat Oncol
Pays: England
ID NLM: 101265111

Informations de publication

Date de publication:
02 Nov 2020
Historique:
received: 02 09 2020
accepted: 24 09 2020
entrez: 3 11 2020
pubmed: 4 11 2020
medline: 4 8 2021
Statut: epublish

Résumé

We read the article entitled "Patterns of brain metastasis immediately before prophylactic cranial irradiation (PCI): implications for PCI optimization in limited-stage small cell lung cancer" with great interest. In that study, the author reported about the importance of PCI timing in limited stage small cell lung cancer (LS-SCLC) in the era of MRI surveillance. In addition, the authors raise the issue of neurotoxicity of PCI. In this letter, we aimed to clarify the value of PCI in LS-SCLC and present ongoing trials regarding PCI and MRI surveillance in SCLC. As a result, we see the need for the development of a prediction tool to estimate the risk of intracranial relapse in LS-SCLC after chemoradiotherapy in order to support shared decision making through improved guidance.

Identifiants

pubmed: 33138845
doi: 10.1186/s13014-020-01680-7
pii: 10.1186/s13014-020-01680-7
pmc: PMC7607688
doi:

Types de publication

Letter

Langues

eng

Sous-ensembles de citation

IM

Pagination

252

Références

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Pract Radiat Oncol. 2020 May - Jun;10(3):158-173
pubmed: 32222430
Cancer. 2008 Apr 15;112(8):1827-34
pubmed: 18311784
Lung Cancer (Auckl). 2018 Aug 16;9:49-55
pubmed: 30323698
Oncotarget. 2018 Apr 3;9(25):17664-17674
pubmed: 29707139
Radiat Oncol. 2019 Sep 18;14(1):171
pubmed: 31533763
Int J Radiat Oncol Biol Phys. 1998 Mar 1;40(4):797-806
pubmed: 9531363
BMC Cancer. 2015 Aug 15;15:589
pubmed: 26275617
N Engl J Med. 1999 Aug 12;341(7):476-84
pubmed: 10441603

Auteurs

Lukas Käsmann (L)

Department of Radiation Oncology, University Hospital LMU Munich, Munich, Germany. LKaesmann@gmail.com.
German Center for Lung Research (DZL), Partner Site Munich, Munich, Germany. LKaesmann@gmail.com.
German Cancer Consortium (DKTK), Munich, Germany. LKaesmann@gmail.com.

Chukwuka Eze (C)

Department of Radiation Oncology, University Hospital LMU Munich, Munich, Germany.
German Center for Lung Research (DZL), Partner Site Munich, Munich, Germany.

Julian Taugner (J)

Department of Radiation Oncology, University Hospital LMU Munich, Munich, Germany.
German Center for Lung Research (DZL), Partner Site Munich, Munich, Germany.

Farkhad Manapov (F)

Department of Radiation Oncology, University Hospital LMU Munich, Munich, Germany.
German Center for Lung Research (DZL), Partner Site Munich, Munich, Germany.
German Cancer Consortium (DKTK), Munich, Germany.

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