Inspiratory stridor of newborns and infants admitted to a paediatric ENT outpatient clinic: diagnostic approach and therapeutic outcome.


Journal

European journal of pediatrics
ISSN: 1432-1076
Titre abrégé: Eur J Pediatr
Pays: Germany
ID NLM: 7603873

Informations de publication

Date de publication:
Apr 2021
Historique:
received: 04 09 2020
accepted: 26 10 2020
revised: 21 10 2020
pubmed: 4 11 2020
medline: 24 6 2021
entrez: 3 11 2020
Statut: ppublish

Résumé

The main objective was to analyse the use of rigid laryngotracheoscopy under general anaesthesia (GA) and endoscopic surgery in the management of inspiratory stridor in patients referred to a paediatric ENT outpatient clinic. The secondary objective was to analyse the aetiological diagnoses made and their therapeutic management. This is a prospective study including all newborns and infants, corresponding to 190 patients, presenting for the first time in consultation for inspiratory stridor from January 2015 to December 2017. A consultation form was filled out after each consultation and added to a database; a management algorithm was used to determine which patients required a rigid laryngotracheoscopy. A 17.9% (n = 34) of the patients required rigid laryngotracheoscopy, of whom 12.6% (n = 24) underwent concomitant endoscopic surgery. A 65.8% (n = 125) of the patients were diagnosed with laryngomalacia, 21.1% (n = 40) with isolated posterior excess of mucosa, 9.5% (n = 18) with another diagnosis and 3.7% (n = 7) with a normal examination. The presence of comorbidity was associated (p < 0.001) with the use of rigid laryngotracheoscopy and endoscopic surgery.Conclusion: Rigid laryngotracheoscopy under GA was required in one in five to six patients. Conservative management with strict follow-up may be appropriate in a large number of patients, especially those with laryngomalacia. What is Known: • Previous research has established that laryngomalacia is the main aetiology of stridor. • Comorbidities are linked with a poor tolerance of stridor. What is new: • About one in five to six patients seen in consultation for stridor will require a trip to the operative room (and one in eight will require endoscopic surgery). • Laryngomalacia and isolated posterior excess of mucosa account for 85-90% of the patients seen in consultation for stridor.

Identifiants

pubmed: 33140202
doi: 10.1007/s00431-020-03858-3
pii: 10.1007/s00431-020-03858-3
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1177-1183

Références

Ida JB, Thompson DM (2014) Pediatric stridor. Otolaryngol Clin N Am 47:795–819
doi: 10.1016/j.otc.2014.06.005
Mondain M, Blanchet C (2010) Stridor or not stridor. Arch Pediatr 17:602–603
doi: 10.1016/S0929-693X(10)70018-X
Thornton AJ, Morley CJ, Hewson PH, Cole TJ, Fowler MA, Tunnacliffe JM (1990) Symptoms in 298 infants under 6 months old, seen at home. Arch Dis Child 65:280–285
doi: 10.1136/adc.65.3.280
Zoumalan R, Maddalozzo J, Holinger LD (2007) Etiology of stridor in infants. Ann Otol Rhinol Laryngol 116:329–334
doi: 10.1177/000348940711600503
Botma M, Kishore A, Kubba H, Geddes N (2000) The role of fibreoptic laryngoscopy in infants with stridor. Int J Pediatr Otorhinolaryngol 55:17–20
doi: 10.1016/S0165-5876(00)00366-9
Holinger LD (1980) Etiology of stridor in the neonate, infant and child. Ann Otol Rhinol Laryngol 89:397–400
doi: 10.1177/000348948008900502
Carter J, Rahbar R, Brigger M, Chan K, Cheng A, Daniel SJ, De Alarcon A et al (2016) International Pediatric ORL Group (IPOG) laryngomalacia consensus recommendations. Int J Pediatr Otorhinolaryngol 86:256–261
doi: 10.1016/j.ijporl.2016.04.007
Thompson DM (2010) Laryngomalacia: factors that influence disease severity and outcomes of management. Curr Opin Otolaryngol Head Neck Surg 18:564–570
doi: 10.1097/MOO.0b013e3283405e48
Ioannidis JPA (2018) The proposal to lower P value thresholds to .005. JAMA 319:1429–1430
doi: 10.1001/jama.2018.1536
Ayari S, Aubertin G, Girschig H, Van Den Abbeele T, Mondain M (2012) Pathophysiology and diagnostic approach to laryngomalacia in infants. Eur Ann Otorhinolaryngol Head Neck Dis 129:257–263
doi: 10.1016/j.anorl.2012.03.005
Mancuso RF (1996) Stridor in neonates. Pediatr Clin N Am 43:1339–1356
doi: 10.1016/S0031-3955(05)70522-8
Denoyelle F, Mondain M, Gresillon N, Roger G, Chaudre F, Garabedian EN (2003) Failures and complications of supraglottoplasty in children. Arch Otolaryngol Head Neck Surg 129:1077–1080
doi: 10.1001/archotol.129.10.1077
Landry AM, Thompson DM (2012) Laryngomalacia: disease presentation, spectrum, and management. Int J Pediatr 2012:753526
doi: 10.1155/2012/753526
Ribeiro J, Julio S, Dias C, Santos M, Spratley J (2018) Supraglottoplasty in children with laryngomalacia: a review and parents’ appraisal. Am J Otolaryngol 39:613–617
doi: 10.1016/j.amjoto.2018.05.007
Shirley F, Oshri W, Ari D, Gad F (2019) The role of laryngeal ultrasound in the assessment of pediatric dysphonia and stridor. Int J Pediatr Otorhinolaryngol 122:175–179
doi: 10.1016/j.ijporl.2019.04.017
Hartl TT, Chadha NK (2012) A systematic review of laryngomalacia and acid reflux. Otolaryngol Head Neck Surg 147:619–626
doi: 10.1177/0194599812452833
Klimara MJ, Samuels TL, Johnston N, Chun RH, McCormick ME (2020) Detection of pepsin in oral secretions of infants with and without laryngomalacia. Ann Otol Rhinol Laryngol 129:224–229
doi: 10.1177/0003489419884332
Luebke K, Samuels TL, Chelius TH, Sulman CG, McCormick ME, Kerschner JE, Johnston N, Chun RH (2017) Pepsin as a biomarker for laryngopharyngeal reflux in children with laryngomalacia. Laryngoscope 127:2413–2417
doi: 10.1002/lary.26537
Matthews BL, Little JP, McGuirt WF Jr, Koufman JA (1999) Reflux in infants with laryngomalacia: results of 24-hour double-probe pH monitoring. Otolaryngol Head Neck Surg 120:860–864
doi: 10.1016/S0194-5998(99)70327-X
Denoyelle F, Garabedian EN, Roger G, Tashjian G (1996) Laryngeal dyskinesia as a cause of stridor in infants. Arch Otolaryngol Head Neck Surg 122:612–616
doi: 10.1001/archotol.1996.01890180020007
Bibi H, Khvolis E, Shoseyov D, Ohaly M, Ben Dor D, London D, Ater D (2001) The prevalence of gastroesophageal reflux in children with tracheomalacia and laryngomalacia. Chest 119:409–413
doi: 10.1378/chest.119.2.409
Halstead LA (1999) Gastroesophageal reflux: a critical factor in pediatric subglottic stenosis. Otolaryngol Head Neck Surg 120:683–688
doi: 10.1053/hn.1999.v120.a91766
Cohen S, Bueno de Mesquita M, Mimouni FB (2015) Adverse effects reported in the use of gastroesophageal reflux disease treatments in children: a 10 years literature review. Br J Clin Pharmacol 80:200–208
doi: 10.1111/bcp.12619
De Bruyne P, Ito S (2018) Toxicity of long-term use of proton pump inhibitors in children. Arch Dis Child 103:78–82
doi: 10.1136/archdischild-2017-314026

Auteurs

Eric Moreddu (E)

Paediatric Otorhinolaryngology, Head and Neck Surgery Department, La Timone Children's Hospital, Aix-Marseille University, 264 rue Saint Pierre, 13385, Marseille Cedex 5, France. eric.moreddu@ap-hm.fr.

Maeva Montero (M)

Otorhinolaryngology, Head and Neck Surgery Department, CHU Clermont-Ferrand, Université Clermont Auvergne, Clermont-Ferrand, France.

Laurent Gilain (L)

Otorhinolaryngology, Head and Neck Surgery Department, CHU Clermont-Ferrand, Université Clermont Auvergne, Clermont-Ferrand, France.

Jean-Michel Triglia (JM)

Paediatric Otorhinolaryngology, Head and Neck Surgery Department, La Timone Children's Hospital, Aix-Marseille University, 264 rue Saint Pierre, 13385, Marseille Cedex 5, France.

Richard Nicollas (R)

Paediatric Otorhinolaryngology, Head and Neck Surgery Department, La Timone Children's Hospital, Aix-Marseille University, 264 rue Saint Pierre, 13385, Marseille Cedex 5, France.

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