Intravascular BOLD signal characterization of balanced SSFP experiments in human blood at high to ultrahigh fields.
BOLD
bSSFP
fMRI
high to ultrahigh fields
human blood
intravascular contribution
Journal
Magnetic resonance in medicine
ISSN: 1522-2594
Titre abrégé: Magn Reson Med
Pays: United States
ID NLM: 8505245
Informations de publication
Date de publication:
04 2021
04 2021
Historique:
received:
02
07
2020
revised:
08
10
2020
accepted:
09
10
2020
pubmed:
4
11
2020
medline:
15
5
2021
entrez:
3
11
2020
Statut:
ppublish
Résumé
To investigate the intravascular contribution to the overall balanced SSFP (bSSFP) BOLD effect in human blood at high to ultrahigh field strengths (3 T, 9.4 T, and 14.1 T). Venous blood prepared at two different oxygenation levels (deoxygenated: Y ≈ 71%, oxygenated: Y ≈ 94%) was measured with phase-cycled bSSFP for varying TRs/flip angles at 3 T, 9.4 T, and 14.1 T. The oxygen sensitivity was analyzed by intrinsic MIRACLE (motion-insensitive rapid configuration relaxometry)-R The MIRACLE-R The results indicate that intravascular effects have to be considered to better understand the origin of bSSFP BOLD contrast in functional MRI experiments, especially at short TRs. The MIRACLE-R
Substances chimiques
Oxygen
S88TT14065
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
2055-2068Informations de copyright
© 2020 The Authors. Magnetic Resonance in Medicine published by Wiley Periodicals LLC on behalf of International Society for Magnetic Resonance in Medicine.
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