Chest Computed Tomography Scoring in Patients With Novel Coronavirus-infected Pneumonia: Correlation With Clinical and Laboratory Features and Disease Outcome.
Aged
Aged, 80 and over
Betacoronavirus
/ pathogenicity
COVID-19
Coronavirus Infections
/ diagnostic imaging
Female
Hospitalization
Humans
Intensive Care Units
Male
Middle Aged
Pandemics
Pneumonia
/ diagnostic imaging
Pneumonia, Viral
/ diagnostic imaging
SARS-CoV-2
Thorax
/ diagnostic imaging
Tomography, X-Ray Computed
Novel coronavirus-infected pneumonia
computer tomography
death
intensive care unit
radiological scores
Journal
In vivo (Athens, Greece)
ISSN: 1791-7549
Titre abrégé: In Vivo
Pays: Greece
ID NLM: 8806809
Informations de publication
Date de publication:
Historique:
received:
16
09
2020
revised:
23
09
2020
accepted:
24
09
2020
entrez:
4
11
2020
pubmed:
5
11
2020
medline:
18
11
2020
Statut:
ppublish
Résumé
This study investigated the correlation of chest computed tomography (CT), findings, graded using two different scoring methods, with clinical and laboratory features and disease outcome, including a novel clinical predictive score, in patients with novel coronavirus-infected pneumonia (NCIP). In this retrospective, observational study, CT scan of 92 NCIP patients admitted to Policlinico Tor Vergata, were analyzed using a quantitative, computed-based and a semiquantitative, radiologist-assessed scoring system. Correlations of the two radiological scores with clinical and laboratory features, the CALL score, and their association with a composite adverse outcome were assessed. The two scores correlated significantly with each other (ρ=0.637, p<0.0001) and were independently associated with age, LDH, estimated glomerular filtration rate, diabetes, and with the composite outcome, which occurred in 24 patients. In NCIP patients, two different radiological scores correlated with each other and with several clinical, laboratory features, and the CALL score. The quantitative score was a better independent predictor of the composite adverse outcome than the semiquantitative score.
Sections du résumé
BACKGROUND/AIM
OBJECTIVE
This study investigated the correlation of chest computed tomography (CT), findings, graded using two different scoring methods, with clinical and laboratory features and disease outcome, including a novel clinical predictive score, in patients with novel coronavirus-infected pneumonia (NCIP).
PATIENTS AND METHODS
METHODS
In this retrospective, observational study, CT scan of 92 NCIP patients admitted to Policlinico Tor Vergata, were analyzed using a quantitative, computed-based and a semiquantitative, radiologist-assessed scoring system. Correlations of the two radiological scores with clinical and laboratory features, the CALL score, and their association with a composite adverse outcome were assessed.
RESULTS
RESULTS
The two scores correlated significantly with each other (ρ=0.637, p<0.0001) and were independently associated with age, LDH, estimated glomerular filtration rate, diabetes, and with the composite outcome, which occurred in 24 patients.
CONCLUSION
CONCLUSIONS
In NCIP patients, two different radiological scores correlated with each other and with several clinical, laboratory features, and the CALL score. The quantitative score was a better independent predictor of the composite adverse outcome than the semiquantitative score.
Identifiants
pubmed: 33144492
pii: 34/6/3735
doi: 10.21873/invivo.12223
pmc: PMC7811662
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
3735-3746Informations de copyright
Copyright© 2020, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.
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