In Vitro
Mannose-6-phosphate
Mannosyl-phosphorylation
Mnn14
enzyme replacement therapy
lysosomal storage disease
Journal
Journal of microbiology and biotechnology
ISSN: 1738-8872
Titre abrégé: J Microbiol Biotechnol
Pays: Korea (South)
ID NLM: 9431852
Informations de publication
Date de publication:
28 Jan 2021
28 Jan 2021
Historique:
received:
14
10
2020
revised:
21
10
2020
accepted:
22
10
2020
pubmed:
5
11
2020
medline:
7
7
2021
entrez:
4
11
2020
Statut:
ppublish
Résumé
Enzyme replacement therapy for lysosomal storage diseases usually requires recombinant enzymes containing mannose-6-phosphate (M6P) glycans for cellular uptake and lysosomal targeting. For the first time, a strategy is established here for the in vitro mannosyl-phosphorylation of high-mannose type
Identifiants
pubmed: 33144549
pii: jmb.2010.10033
doi: 10.4014/jmb.2010.10033
pmc: PMC9705852
doi:
Substances chimiques
Mannosephosphates
0
Polysaccharides
0
Recombinant Proteins
0
Saccharomyces cerevisiae Proteins
0
mannose-6-phosphate
3672-15-9
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
163-170Références
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