Characterization of Synovial Cytokine Patterns in Bucket-Handle and Posterior Horn Meniscal Tears.
Journal
Mediators of inflammation
ISSN: 1466-1861
Titre abrégé: Mediators Inflamm
Pays: United States
ID NLM: 9209001
Informations de publication
Date de publication:
2020
2020
Historique:
received:
08
06
2020
revised:
23
09
2020
accepted:
15
10
2020
entrez:
4
11
2020
pubmed:
5
11
2020
medline:
7
10
2021
Statut:
epublish
Résumé
The specific etiology of meniscal tears, including the mechanism of lesion, location, and orientation, is considered for its contribution to subsequent joint cytokine responsiveness, healing outcomes, and by extension, appropriate lesion-specific surgical remediation. Meniscal repair is desirable to reduce the probability of development of posttraumatic osteoarthritis (PTOA) which is strongly influenced by the coordinate generation of pro- and anti-inflammatory cytokines by the injured cartilage. We now present biochemical data on variation in cytokine levels arising from two particular meniscal tears: bucket-handle (BH) and posterior horn (PH) isolated meniscal tears. We selected these two groups due to the different clinical presentations. We measured the concentrations of TNF-
Identifiants
pubmed: 33144846
doi: 10.1155/2020/5071934
pmc: PMC7599409
doi:
Substances chimiques
Interleukin-8
0
Tumor Necrosis Factor-alpha
0
Interleukin-10
130068-27-8
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
5071934Informations de copyright
Copyright © 2020 Marco Turati et al.
Déclaration de conflit d'intérêts
None of the authors have any conflicts of interest to declare.
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