Endoclip papillaplasty restores sphincter of Oddi function: Pilot study.


Journal

Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society
ISSN: 1443-1661
Titre abrégé: Dig Endosc
Pays: Australia
ID NLM: 9101419

Informations de publication

Date de publication:
Sep 2021
Historique:
revised: 28 10 2020
received: 25 06 2020
accepted: 02 11 2020
pubmed: 5 11 2020
medline: 8 9 2021
entrez: 4 11 2020
Statut: ppublish

Résumé

Endoscopic sphincterotomy (EST) damaged the sphincter of Oddi (SO) function. This study aimed to explore the feasibility and efficacy of endoclip papillaplasty in restoring SO function. This prospective pilot study included consecutive patients with choledocholithiasis (stone size ≥10 mm) who underwent large-EST for stone removal, followed by endoclip papillaplasty, between May 2018 and March 2019. Thirty patients were enrolled in this trail. Overall, 80% of the patients had a SO basal pressure of >10 mmHg after endoclip papillaplasty. Manometric parameters, including SO basal pressure, phasic wave contraction amplitude, phasic waves per minute, recovered after endoclip papillaplasty (P > 0.05). There were no significant differences in the manometric parameters of SO between healing grades A and B. Six patients developed mild post-endoscopic retrograde cholangiopancreatography pancreatitis, including three that had pancreatic stenting. Bile duct stone recurrence developed in 3.3% of the patients (1/30) during an 18-month follow-up. Endoclip papillaplasty might restore SO function and possibly prevented biliary stone and cholangitis recurrence.

Identifiants

pubmed: 33145797
doi: 10.1111/den.13887
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

962-969

Subventions

Organisme : National Natural Science Foundation of China
ID : 81470905
Organisme : Beijing Science and Technology Commission
ID : Z181100001718149

Informations de copyright

© 2020 Japan Gastroenterological Endoscopy Society.

Références

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Auteurs

Xiue Yan (X)

The Department of Gastroenterology and Hepatology, Peking University Third Hospital, Beijing, China.

Wei Zheng (W)

The Department of Gastroenterology and Hepatology, Peking University Third Hospital, Beijing, China.

Yaopeng Zhang (Y)

The Department of Gastroenterology and Hepatology, Peking University Third Hospital, Beijing, China.

Hong Chang (H)

The Department of Gastroenterology and Hepatology, Peking University Third Hospital, Beijing, China.

Kun Wang (K)

The Department of Gastroenterology and Hepatology, Peking University Third Hospital, Beijing, China.

Xin Li (X)

Department of Gastroenterology, Peking University International Hospital, Beijing, China.

Hejun Zhang (H)

The Department of Gastroenterology and Hepatology, Peking University Third Hospital, Beijing, China.

Yingchun Wang (Y)

The Department of Gastroenterology and Hepatology, Peking University Third Hospital, Beijing, China.

Wei Yao (W)

The Department of Gastroenterology and Hepatology, Peking University Third Hospital, Beijing, China.

Ke Li (K)

The Department of Gastroenterology and Hepatology, Peking University Third Hospital, Beijing, China.

Yonghui Huang (Y)

The Department of Gastroenterology and Hepatology, Peking University Third Hospital, Beijing, China.

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