Chest drain aerosol generation in COVID-19 and emission reduction using a simple anti-viral filter.


Journal

BMJ open respiratory research
ISSN: 2052-4439
Titre abrégé: BMJ Open Respir Res
Pays: England
ID NLM: 101638061

Informations de publication

Date de publication:
11 2020
Historique:
received: 11 07 2020
revised: 27 08 2020
accepted: 07 10 2020
entrez: 5 11 2020
pubmed: 6 11 2020
medline: 18 11 2020
Statut: ppublish

Résumé

The COVID-19 pandemic has been characterised by significant in-hospital virus transmission and deaths among healthcare workers. Sources of in-hospital transmission are not fully understood, with special precautions currently reserved for procedures previously shown to generate aerosols (particles <5 μm). Pleural procedures are not currently considered AGPs (Aerosol Generating Procedures), reflecting a lack of data in this area. An underwater seal chest drain bottle (R54500, Rocket Medical UK) was set up inside a 60-litre plastic box and connected via an airtight conduit to a medical air supply. A multichannel particle counter (TSI Aerotrak 9310 Aerosol Monitor) was placed inside the box, allowing measurement of particle count/cubic foot (pc/ft Aerosol emissions increased with increasing air flow, with the largest increase observed in smaller particles (0.3-3 μm). Concentration of the smallest particles (0.3-0.5 μm) increased from background levels by 700, 1400 and 2500 pc/ft A bubbling chest drain is a source of aerosolised particles, but emission can be prevented using a simple anti-viral filter. These data should be considered when designing measures to reduce in-hospital spread of SARS-CoV-2.

Identifiants

pubmed: 33148778
pii: 7/1/e000710
doi: 10.1136/bmjresp-2020-000710
pmc: PMC7643431
pii:
doi:

Substances chimiques

Aerosols 0
Particulate Matter 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

Déclaration de conflit d'intérêts

Competing interests: KGB has received research funding from Rocket Medical UK for other studies.

Références

Clin Med (Lond). 2020 Jul;20(4):e60-e61
pubmed: 32457134
Chest. 2020 Oct;158(4):e143-e146
pubmed: 32534909
Trauma Surg Acute Care Open. 2020 Apr 30;5(1):e000498
pubmed: 32411822
JAMA. 2020 Jun 23;323(24):2518-2520
pubmed: 32437497
Curr Med Sci. 2020 Apr;40(2):295-300
pubmed: 32232652
Lancet Infect Dis. 2020 Jun;20(6):697-706
pubmed: 32224310
N Engl J Med. 2020 Apr 16;382(16):1564-1567
pubmed: 32182409

Auteurs

Clodagh Duffy (C)

Medical Devices Unit, NHS Greater Glasgow and Clyde, Glasgow, UK.

Andrew Kidd (A)

Respiratory Medicine, Queen Elizabeth University Hospital, Glasgow, UK.
Institute of Cancer Sciences, University of Glasgow, Glasgow, UK.

Sarah Francis (S)

Medical Devices Unit, NHS Greater Glasgow and Clyde, Glasgow, UK.

Selina Tsim (S)

Respiratory Medicine, Queen Elizabeth University Hospital, Glasgow, UK.
Institute of Cancer Sciences, University of Glasgow, Glasgow, UK.

Laura McNaughton (L)

Respiratory Medicine, Queen Elizabeth University Hospital, Glasgow, UK.

Katie Ferguson (K)

Respiratory Medicine, Queen Elizabeth University Hospital, Glasgow, UK.
Institute of Cancer Sciences, University of Glasgow, Glasgow, UK.

Jenny Ferguson (J)

Respiratory Medicine, Queen Elizabeth University Hospital, Glasgow, UK.
Institute of Cancer Sciences, University of Glasgow, Glasgow, UK.

K Gary Rodgers (KG)

Emergency Department, Queen Elizabeth University Hospital, Glasgow, UK.

Claire McGroarty (C)

Emergency Department, Queen Elizabeth University Hospital, Glasgow, UK.

Robin Sayer (R)

Medical Devices Unit, NHS Greater Glasgow and Clyde, Glasgow, UK.

Kevin G Blyth (KG)

Institute of Cancer Sciences, University of Glasgow, Glasgow, UK kevin.blyth@glasgow.ac.uk.
Glasgow Pleural Disease Unit, Respiratory Medicine, Queen Elizabeth University Hospital, Glasgow, UK.

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Classifications MeSH