Value of photo assessment in late patch test readings-A multicenter study from six European patch test clinics.


Journal

Contact dermatitis
ISSN: 1600-0536
Titre abrégé: Contact Dermatitis
Pays: England
ID NLM: 7604950

Informations de publication

Date de publication:
May 2021
Historique:
revised: 21 10 2020
received: 23 09 2020
accepted: 27 10 2020
pubmed: 6 11 2020
medline: 4 11 2021
entrez: 5 11 2020
Statut: ppublish

Résumé

It is recommended that patch test readings include a day (D)7 reading. Substitution of the D7 reading with a photo may be a valid option. To compare the sensitivity of digital photos at D7 to clinical readings, to assess the number of positive reactions appearing at D7 only (late reactions), and after D7 only (delayed reactions). Patients patch tested in six European clinics were instructed to forward photos of the patch test reactions to the respective clinics at D7 (before attending the clinic) and at D21. Only allergens in the baseline series or TRUE Test were included in the data analysis. Two hundred ninety-three of 629 patients had a total of 599 positive reactions, with 6.3% occurring at D7 only. When substituting the D7 reading with a photo (90% submitted), 26.3% of late reactions were missed and nine false-positive reactions were found. Delayed reactions were detected in four patients at D21 (65.3% submitted). Our data show that if the D7 reading is not performed, 6.3% of positive reactions from the baseline series would be missed, and if substituting the D7 reading by digital photo, 26.3% late reactions would be missed. Delayed reactions seemed rare.

Sections du résumé

BACKGROUND BACKGROUND
It is recommended that patch test readings include a day (D)7 reading. Substitution of the D7 reading with a photo may be a valid option.
OBJECTIVES OBJECTIVE
To compare the sensitivity of digital photos at D7 to clinical readings, to assess the number of positive reactions appearing at D7 only (late reactions), and after D7 only (delayed reactions).
METHODS METHODS
Patients patch tested in six European clinics were instructed to forward photos of the patch test reactions to the respective clinics at D7 (before attending the clinic) and at D21. Only allergens in the baseline series or TRUE Test were included in the data analysis.
RESULTS RESULTS
Two hundred ninety-three of 629 patients had a total of 599 positive reactions, with 6.3% occurring at D7 only. When substituting the D7 reading with a photo (90% submitted), 26.3% of late reactions were missed and nine false-positive reactions were found. Delayed reactions were detected in four patients at D21 (65.3% submitted).
CONCLUSION CONCLUSIONS
Our data show that if the D7 reading is not performed, 6.3% of positive reactions from the baseline series would be missed, and if substituting the D7 reading by digital photo, 26.3% late reactions would be missed. Delayed reactions seemed rare.

Identifiants

pubmed: 33152126
doi: 10.1111/cod.13736
doi:

Types de publication

Journal Article Multicenter Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

283-289

Informations de copyright

© 2020 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

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Auteurs

Yasemin T Yüksel (YT)

Department of Dermatology, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark.

Farnam B Sedeh (FB)

Department of Dermatology, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark.

Richard Brans (R)

Department of Dermatology, Environmental Medicine and Health Theory, University of Osnabrück, Osnabrück, Germany.

Cecilia Svedman (C)

Department of Occupational Dermatology, University of Lund, Skåne University Hospital, Malmö, Sweden.

Evy Paulsen (E)

Department of Dermatology and Allergy Centre, Odense University Hospital, University of Southern Denmark, Odense, Denmark.

Ana Gimenéz-Arnau (A)

Department of Dermatology, Hospital del Mar, IMIM, Universitat Autònoma de Barcelona, Barcelona, Spain.

Caterina Foti (C)

Department of Biomedical Science and Human Oncology, Dermatological Clinic, University of Bari, Bari, Italy.

Tove Agner (T)

Department of Dermatology, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark.

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