CRISPR/Cas13: A potential therapeutic option of COVID-19.
Betacoronavirus
/ drug effects
COVID-19
CRISPR-Associated Proteins
/ pharmacology
CRISPR-Cas Systems
Conserved Sequence
Coronavirus Infections
/ drug therapy
Gene Editing
Genetic Therapy
/ methods
Genome, Viral
Humans
Pandemics
Pneumonia, Viral
/ genetics
RNA, Guide, Kinetoplastida
/ genetics
RNA, Viral
/ antagonists & inhibitors
SARS-CoV-2
COVID-19 Drug Treatment
COVID-19
CRISPR/Cas13
CRISPR/dead Cas13
SARS-CoV-2
Treatment
Journal
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
ISSN: 1950-6007
Titre abrégé: Biomed Pharmacother
Pays: France
ID NLM: 8213295
Informations de publication
Date de publication:
Nov 2020
Nov 2020
Historique:
received:
14
06
2020
revised:
27
08
2020
accepted:
07
09
2020
entrez:
6
11
2020
pubmed:
7
11
2020
medline:
18
11
2020
Statut:
ppublish
Résumé
The novel coronavirus called severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can be considered as the most important current global issue, as it has caused the novel coronavirus disease (COVID-19) pandemic, which has resulted in high mortality and morbidity rates all around the world. Although scientists are trying to discover novel therapies and develop and evaluate various previous treatments, at the time of writing this paper, there was no definite therapy and vaccine for COVID-19. So, as COVID-19 has called ideas for treatment, controlling, and diagnosis, we discussed the application of Clustered Regularly Interspaced Short Palindromic Repeats/Cas13 (CRISPR/Cas13) as a treatment of COVID-19, which received less attention compared with other potential therapeutic options.
Identifiants
pubmed: 33152914
pii: S0753-3322(20)30931-8
doi: 10.1016/j.biopha.2020.110738
pmc: PMC7498250
pii:
doi:
Substances chimiques
CRISPR-Associated Proteins
0
RNA, Guide
0
RNA, Viral
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
110738Informations de copyright
Copyright © 2020 The Authors. Published by Elsevier Masson SAS.. All rights reserved.
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