Model-based Material Decomposition with System Blur Modeling.


Journal

Proceedings of SPIE--the International Society for Optical Engineering
ISSN: 0277-786X
Titre abrégé: Proc SPIE Int Soc Opt Eng
Pays: United States
ID NLM: 101524122

Informations de publication

Date de publication:
Feb 2020
Historique:
entrez: 6 11 2020
pubmed: 7 11 2020
medline: 7 11 2020
Statut: ppublish

Résumé

In this work, we present a novel model-based material decomposition (MBMD) approach for x-ray CT that includes system blur in the measurement model. Such processing has the potential to extend spatial resolution in material density estimates - particularly in systems where different spectral channels exhibit different spatial resolutions. We illustrate this new approach for a dual-layer detector x-ray CT and compare MBMD algorithms with and without blur in the reconstruction forward model. Both qualitative and quantitative comparisons of performance with and without blur modeling are reported. We find that blur modeling yields images with better recovery of high-resolution structures in an investigation of reconstructed line pairs as well as lower cross-talk bias between material bases that is ordinarily found due to mismatches in spatial resolution between spectral channels. The extended spatial resolution of the material decompositions has potential application in a range of high-resolution clinical tasks and spectral CT systems where spectral channels exhibit different spatial resolutions.

Identifiants

pubmed: 33154609
doi: 10.1117/12.2549549
pmc: PMC7641016
mid: NIHMS1640729
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : NIBIB NIH HHS
ID : R01 EB025470
Pays : United States
Organisme : NIGMS NIH HHS
ID : T32 GM007057
Pays : United States

Références

Med Phys. 2016 Aug;43(8):4711
pubmed: 27487888
IEEE Trans Med Imaging. 2018 Apr;37(4):988-999
pubmed: 29621002
Phys Med Biol. 2019 Jan 22;64(3):035005
pubmed: 30561382

Auteurs

Wenying Wang (W)

Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD 21205.

Matthew Tivnan (M)

Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD 21205.

Grace J Gang (GJ)

Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD 21205.

Yiqun Ma (Y)

Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD 21205.

Qian Cao (Q)

Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD 21205.

Minghui Lu (M)

Varex Imaging Corp., 683 River Oaks Pkwy, San Jose, CA 95134.

Josh Star-Lack (J)

Varex Imaging Corp., 683 River Oaks Pkwy, San Jose, CA 95134.

Richard E Colbeth (RE)

Varex Imaging Corp., 683 River Oaks Pkwy, San Jose, CA 95134.

Wojciech Zbijewski (W)

Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD 21205.

J Webster Stayman (JW)

Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD 21205.

Classifications MeSH