Poly(

Antimalarials / administration & dosage Drug Delivery Systems Peptides Polymerization Polymers Pyrrolidinones

Journal

Biomacromolecules
ISSN: 1526-4602
Titre abrégé: Biomacromolecules
Pays: United States
ID NLM: 100892849

Informations de publication

Date de publication:
14 12 2020
Historique:
pubmed: 7 11 2020
medline: 25 5 2021
entrez: 6 11 2020
Statut: ppublish

Résumé

The concepts of polymer-peptide conjugation and self-assembly were applied to antimicrobial peptides (AMPs) in the development of a targeted antimalaria drug delivery construct. This study describes the synthesis of α-acetal, ω-xanthate heterotelechelic poly(

Identifiants

DOI: 10.1021/acs.biomac.0c01202 PMID: 33156615
pubmed: 33156615
doi: 10.1021/acs.biomac.0c01202
doi:

Substances chimiques

Antimalarials 0
Peptides 0
Polymers 0
Pyrrolidinones 0
N-vinyl-2-pyrrolidinone 76H9G81541

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

5053-5066

Auteurs

Simbarashe Jokonya (S)

Department of Chemistry and Polymer Science, Stellenbosch University, Private Bag X1, Matieland 7602, South Africa.

Marvin Langlais (M)

Department of Chemistry and Polymer Science, Stellenbosch University, Private Bag X1, Matieland 7602, South Africa.

Meta Leshabane (M)

Department of Biochemistry, Genetics and Microbiology, Institute of Sustainable Malaria Control, University of Pretoria, Private Bag X20, Hatfield 0028, South Africa.

Paul W Reader (PW)

Department of Chemistry and Polymer Science, Stellenbosch University, Private Bag X1, Matieland 7602, South Africa.

Johan A Vosloo (JA)

BioPep Peptide Group, Department of Biochemistry, Stellenbosch University, Private Bag X1, Matieland 7602, South Africa.

Rueben Pfukwa (R)

Department of Chemistry and Polymer Science, Stellenbosch University, Private Bag X1, Matieland 7602, South Africa.

Dina Coertzen (D)

Department of Biochemistry, Genetics and Microbiology, Institute of Sustainable Malaria Control, University of Pretoria, Private Bag X20, Hatfield 0028, South Africa.

Lyn-Marie Birkholtz (LM)

Department of Biochemistry, Genetics and Microbiology, Institute of Sustainable Malaria Control, University of Pretoria, Private Bag X20, Hatfield 0028, South Africa.

Marina Rautenbach (M)

BioPep Peptide Group, Department of Biochemistry, Stellenbosch University, Private Bag X1, Matieland 7602, South Africa.

Bert Klumperman (B)

Department of Chemistry and Polymer Science, Stellenbosch University, Private Bag X1, Matieland 7602, South Africa.
ORCID: 0000-0003-1561-274X

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Classifications MeSH

questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Anti-infectieux › Antiparasitaires › Antiprotozoaires › Antipaludiques › Poly(
questionsmedicales.fr › Thérapeutique › Traitement médicamenteux › Systèmes de délivrance de médicaments › Poly(
questionsmedicales.fr › Acides aminés, peptides et protéines › Peptides › Poly(
questionsmedicales.fr › Phénomènes chimiques › Polymérisation › Poly(
questionsmedicales.fr › Technologie, industrie et agriculture › Produits manufacturés › Matériaux biomédicaux et dentaires › Polymères › Poly(
questionsmedicales.fr › Composés hétérocycliques › Composés hétéromonocycliques › Pyrrolidines › Pyrrolidones › Poly(