Esophageal balloon calibration during Sigh: A physiologic, randomized, cross-over study.

Optimal esophageal balloon filling volume (V Twenty adult patients requiring invasive volume-controlled ventilation (VCV) for hypoxemic acute respiratory failure were enrolled. After the insertion of a naso-gastric catheter equipped with 10 ml esophageal balloon, each patient underwent three 30-min trials as follows: VCV, pressure support ventilation (PSV), and PSV + Sigh. Sigh was added to PSV as 35 cmH V During Sigh breath, applying a calibrated approach for Pes assessment, a higher V

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Déclaration de conflit d'intérêts

Declaration of Competing Interest No conflict of interest exists for Gianmaria Cammarota, Erminio Santangelo, Gianluigi Lauro, Federico Verdina, Ester Boniolo, Riccardo Tarquini, Elena Spinelli, Eugenio Garofalo, Andrea Bruni, Marta Zanoni, Francesco Della Corte, and Rosanna Vaschetto. Prof. Paolo Navalesi reports grants, personal fees and non-financial support from Maquet Critical Care, grants and non-financial support from Draeger, grants and non-financial support from Intersurgical S.p.A, personal fees from Oriopharma, personal fees from Philips, personal fees from Resmed, personal fees from MSD, personal fees from Novartis, outside the submitted work. In addition, Prof. Navalesi has a patent helmet Next with royalties paid to Intersurgical Spa, and a patent EP20170199831 pending. Dr. Messina reports personal fees and other from Vygon, outside the submitted work. Prof. Pesenti reports personal fees from Maquet, personal fees from Xenios, personal fees from Baxter, personal fees from Boehringer Ingelheim, outside the submitted work. Dr. Mauri reports personal fees from Drager, personal fees from Fisher and Paykel, outside the submitted work.