Angio-Based Index of Microcirculatory Resistance for the Assessment of the Coronary Resistance: A Proof of Concept Study.
Journal
Journal of interventional cardiology
ISSN: 1540-8183
Titre abrégé: J Interv Cardiol
Pays: United States
ID NLM: 8907826
Informations de publication
Date de publication:
2020
2020
Historique:
received:
16
07
2020
accepted:
14
10
2020
entrez:
9
11
2020
pubmed:
10
11
2020
medline:
10
4
2021
Statut:
epublish
Résumé
The study of coronary microcirculation has gained increasing consideration and importance in cath lab. Despite the increase of evidence, its use still remains very limited. QFR is a novel angio-based approach for the evaluation of coronary stenosis. The aim of our study was to use the QFR assessment in stable patients to recreate the IMR formula and to correlate the result of the two techniques. From June 1, 2019, to February 29, 2019, 200 patients with CCS and indication of coronary artery angiography and referred to the cath lab of the University Hospital of Ferrara (Italy) were enrolled. After baseline coronary angiogram, quantitative flow ratio, fractional flow reserve, and index of microcirculatory resistance evaluation were performed. Pearson correlation ( We have validated for the first time the formula of the A-IMR, a tool for the calculation of microvascular resistance which does not require the use of pressure guides and the induction of hyperemia.
Sections du résumé
BACKGROUND
BACKGROUND
The study of coronary microcirculation has gained increasing consideration and importance in cath lab. Despite the increase of evidence, its use still remains very limited. QFR is a novel angio-based approach for the evaluation of coronary stenosis. The aim of our study was to use the QFR assessment in stable patients to recreate the IMR formula and to correlate the result of the two techniques.
METHODS
METHODS
From June 1, 2019, to February 29, 2019, 200 patients with CCS and indication of coronary artery angiography and referred to the cath lab of the University Hospital of Ferrara (Italy) were enrolled. After baseline coronary angiogram, quantitative flow ratio, fractional flow reserve, and index of microcirculatory resistance evaluation were performed.
RESULTS
RESULTS
Pearson correlation (
CONCLUSION
CONCLUSIONS
We have validated for the first time the formula of the A-IMR, a tool for the calculation of microvascular resistance which does not require the use of pressure guides and the induction of hyperemia.
Identifiants
pubmed: 33162844
doi: 10.1155/2020/8887369
pmc: PMC7605930
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
8887369Informations de copyright
Copyright © 2020 Matteo Tebaldi et al.
Déclaration de conflit d'intérêts
Tebaldi Matteo received speaking honoraria from Abbott. The other authors have no conflicts of interest to disclose.
Références
JACC Cardiovasc Interv. 2013 Jan;6(1):53-8
pubmed: 23347861
JACC Cardiovasc Interv. 2016 Oct 10;9(19):2024-2035
pubmed: 27712739
J Eval Clin Pract. 2004 May;10(2):307-12
pubmed: 15189396
JACC Cardiovasc Imaging. 2019 May;12(5):837-848
pubmed: 29680355
Circulation. 2003 Jul 1;107(25):3129-32
pubmed: 12821539
Eur Heart J. 2020 Jan 14;41(3):407-477
pubmed: 31504439