[Covid-19: clinical aspects and management].
Covid-19 : aspects cliniques et principaux éléments de prise en charge.
Covid-19
chest CT-scan
clinical signs
management
vaccine
Journal
Revue francophone des laboratoires : RFL
ISSN: 1773-035X
Titre abrégé: Rev Francoph Lab
Pays: France
ID NLM: 101264920
Informations de publication
Date de publication:
Nov 2020
Nov 2020
Historique:
entrez:
9
11
2020
pubmed:
10
11
2020
medline:
10
11
2020
Statut:
ppublish
Résumé
Asymptomatic infections are not rare and most patients complain with fever and respiratory signs. Clinical signs are polymorphic and aspecific. Chest CT scan is commonly used as a diagnostic and triage tool in patients admitted to hospitalization. The 2 main complications are respiratory distress related to worsening pneumonia with an associated cytokine storm occurring mostly 7 to 10 days after disease onset, and thromboembolic disease. The fatality rate is around 2%. In-hospital management includes oxygen supply when needed and prevention of thromboembolic disease. Associated bacterial infections seem to be rare. Remdesivir might reduce the time to recovery in hospitalized patients needing an oxygen supply. Dexamethasone might reduce the fatality rate in patients requiring mechanical ventilation. The development of many candidate vaccines gives hope to fight the pandemic.
Identifiants
pubmed: 33163103
doi: 10.1016/S1773-035X(20)30312-9
pii: S1773-035X(20)30312-9
pmc: PMC7603941
doi:
Types de publication
English Abstract
Journal Article
Langues
fre
Pagination
40-47Informations de copyright
Copyright © 2020 Elsevier Masson SAS. All rights reserved.
Références
J Eur Acad Dermatol Venereol. 2020 May;34(5):e212-e213
pubmed: 32215952
N Engl J Med. 2020 Sep 3;383(10):994
pubmed: 32649078
N Engl J Med. 2020 Apr 23;382(17):1663-1665
pubmed: 32187458
Nature. 2020 Jun;582(7813):469
pubmed: 32546811
Lancet Infect Dis. 2020 Jun;20(6):689-696
pubmed: 32220650
Rev Med Suisse. 2020 May 6;16(692):947-949
pubmed: 32374543
N Engl J Med. 2020 May 28;382(22):2163-2164
pubmed: 32283004
Pediatrics. 2020 Aug;146(2):
pubmed: 32439816
JAMA. 2020 Apr 7;323(13):1239-1242
pubmed: 32091533
Am J Respir Crit Care Med. 2020 May 15;201(10):1299-1300
pubmed: 32228035
Clin Infect Dis. 2021 Feb 1;72(3):490-494
pubmed: 32556328
JAMA. 2020 Mar 17;323(11):1061-1069
pubmed: 32031570
Nat Commun. 2020 Jul 14;11(1):3572
pubmed: 32665677
Sci China Life Sci. 2020 May;63(5):706-711
pubmed: 32146694
JAMA. 2020 May 12;323(18):1775-1776
pubmed: 32203977
J Infect. 2020 Jun;80(6):607-613
pubmed: 32283152
Rev Med Suisse. 2020 Apr 29;16(N° 691-2):842-844
pubmed: 32348049
Ann Intern Med. 2020 May 05;172(9):577-582
pubmed: 32150748