[Covid-19: clinical aspects and management].

Covid-19 : aspects cliniques et principaux éléments de prise en charge.
Covid-19 chest CT-scan clinical signs management vaccine

Journal

Revue francophone des laboratoires : RFL
ISSN: 1773-035X
Titre abrégé: Rev Francoph Lab
Pays: France
ID NLM: 101264920

Informations de publication

Date de publication:
Nov 2020
Historique:
entrez: 9 11 2020
pubmed: 10 11 2020
medline: 10 11 2020
Statut: ppublish

Résumé

Asymptomatic infections are not rare and most patients complain with fever and respiratory signs. Clinical signs are polymorphic and aspecific. Chest CT scan is commonly used as a diagnostic and triage tool in patients admitted to hospitalization. The 2 main complications are respiratory distress related to worsening pneumonia with an associated cytokine storm occurring mostly 7 to 10 days after disease onset, and thromboembolic disease. The fatality rate is around 2%. In-hospital management includes oxygen supply when needed and prevention of thromboembolic disease. Associated bacterial infections seem to be rare. Remdesivir might reduce the time to recovery in hospitalized patients needing an oxygen supply. Dexamethasone might reduce the fatality rate in patients requiring mechanical ventilation. The development of many candidate vaccines gives hope to fight the pandemic.

Identifiants

pubmed: 33163103
doi: 10.1016/S1773-035X(20)30312-9
pii: S1773-035X(20)30312-9
pmc: PMC7603941
doi:

Types de publication

English Abstract Journal Article

Langues

fre

Pagination

40-47

Informations de copyright

Copyright © 2020 Elsevier Masson SAS. All rights reserved.

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Auteurs

Édouard Desvaux (É)

Service de médecine interne gériatrique, CHU de limoges, 2, avenue Martin-Luther-King, 87042 Limoges cedex, France.

Jean-François Faucher (JF)

Service de maladies infectieuses et tropicales, CHU de Limoges, 16 rue Bernard-Descottes, 87042 Limoges, France.

Classifications MeSH