COVID-19 Hospitalization in Adults with Type 1 Diabetes: Results from the T1D Exchange Multicenter Surveillance Study.
Adult
Aged
Aged, 80 and over
COVID-19
/ complications
Comorbidity
Cross-Sectional Studies
Diabetes Mellitus, Type 1
/ complications
Female
Hospitalization
/ statistics & numerical data
Humans
Male
Middle Aged
Pandemics
Population Surveillance
Prognosis
Retrospective Studies
SARS-CoV-2
/ physiology
Treatment Outcome
United States
/ epidemiology
Young Adult
COVID-19
adult
hospitalization
type 1 diabetes
Journal
The Journal of clinical endocrinology and metabolism
ISSN: 1945-7197
Titre abrégé: J Clin Endocrinol Metab
Pays: United States
ID NLM: 0375362
Informations de publication
Date de publication:
23 01 2021
23 01 2021
Historique:
received:
09
09
2020
pubmed:
10
11
2020
medline:
28
1
2021
entrez:
9
11
2020
Statut:
ppublish
Résumé
Diabetes mellitus is associated with increased COVID-19 morbidity and mortality, but there are few data focusing on outcomes in people with type 1 diabetes. The objective of this study was to analyze characteristics of adults with type 1 diabetes for associations with COVID-19 hospitalization. An observational multisite cross-sectional study was performed. Diabetes care providers answered a 33-item questionnaire regarding demographics, symptoms, and diabetes- and COVID-19-related care and outcomes. Descriptive statistics were used to describe the study population, and multivariate logistic regression models were used to analyze the relationship between glycated hemoglobin (HbA1c), age, and comorbidities and hospitalization. Cases were submitted from 52 US sites between March and August 2020. Adults over the age of 19 with type 1 diabetes and confirmed COVID-19 infection were included. None. Hospitalization for COVID-19 infection. A total of 113 cases were analyzed. Fifty-eight patients were hospitalized, and 5 patients died. Patients who were hospitalized were more likely to be older, to identify as non-Hispanic Black, to use public insurance, or to have hypertension, and less likely to use continuous glucose monitoring or insulin pumps. Median HbA1c was 8.6% (70 mmol/mol) and was positively associated with hospitalization (odds ratio 1.42, 95% confidence interval 1.18-1.76), which persisted after adjustment for age, sex, race, and obesity. Baseline glycemic control and access to care are important modifiable risk factors which need to be addressed to optimize care of people with type 1 diabetes during the worldwide COVID-19 pandemic.
Identifiants
pubmed: 33165563
pii: 5963916
doi: 10.1210/clinem/dgaa825
pmc: PMC7717244
doi:
Types de publication
Journal Article
Multicenter Study
Observational Study
Langues
eng
Sous-ensembles de citation
IM
Pagination
e936-e942Subventions
Organisme : NIDDK NIH HHS
ID : K23 DK115896
Pays : United States
Organisme : NIDDK NIH HHS
ID : P30 DK111022
Pays : United States
Organisme : NIDDK NIH HHS
ID : T32 DK112751
Pays : United States
Organisme : NIDDK NIH HHS
ID : P30 DK020541
Pays : United States
Organisme : NIDDK NIH HHS
ID : R01 DK097820
Pays : United States
Informations de copyright
© The Author(s) 2020. Published by Oxford University Press on behalf of the Endocrine Society. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.