Change in the geometry of positive- and negative-powered soft contact lenses during wear.
Journal
PloS one
ISSN: 1932-6203
Titre abrégé: PLoS One
Pays: United States
ID NLM: 101285081
Informations de publication
Date de publication:
2020
2020
Historique:
received:
05
07
2020
accepted:
27
10
2020
entrez:
9
11
2020
pubmed:
10
11
2020
medline:
30
12
2020
Statut:
epublish
Résumé
Contact lens wear causes mutual interactions between the ocular surface and the lens, which may affect comfort as well as vision. The aim of this study was to examine deformations in modern positive- and negative-powered silicone hydrogel soft contact lenses (SiH SCLs) after 7 days of continuous wear. This pre-post interventional study included 64 eyes: 42 eyes with myopia of -3.00 D and 22 eyes with hyperopia of +3.00 D. All patients underwent general ophthalmic examination, corneal topography/tomography, total corneal and epithelial thickness mapping, and specular microscopy before and after the wearing period. SiH SCLs made of senofilcon A were worn continuously for 7 days on all eligible eyes. The geometry of the new and used lenses was measured 3 to 6 minutes after removal in two perpendicular planes using a custom-made swept source optical coherence tomography (SS-OCT) system for in vitro measurements. The anterior and posterior radii of curvature decreased in -3.00 D lenses in two perpendicular planes. This effect correlated significantly with average keratometry of the cornea. Sagittal lens height was lower in +3.00 D lens after wear, which correlated moderately with the corneal sagittal height. A significant decrease in central corneal epithelial thickness was observed after wearing +3.0 D lenses. In conclusion, SiH SCLs made of senofilcon A undergo minor deformations after 7-day continuous wear. Geometry modifications are different for -3.00 D and +3.00 D lenses, and they imitate the shape of the anterior eye surface. These geometric changes are accompanied by a decrease in the central thickness of corneal epithelium after +3.00 D lens wear.
Identifiants
pubmed: 33166364
doi: 10.1371/journal.pone.0242095
pii: PONE-D-20-20564
pmc: PMC7652269
doi:
Substances chimiques
Hydrogels
0
Silicones
0
senofilcon A
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e0242095Déclaration de conflit d'intérêts
The authors have declared that no competing interests exist.
Références
Cont Lens Anterior Eye. 2013 Aug;36(4):171-5
pubmed: 23395396
Opt Lett. 2014 Aug 15;39(16):4727-30
pubmed: 25121859
Eye Contact Lens. 2013 Jan;39(1):115-24
pubmed: 23271473
Drug Deliv. 2016 Oct;23(8):3017-3026
pubmed: 26821766
Cont Lens Anterior Eye. 2004 Sep;27(3):115-31
pubmed: 16303535
Cont Lens Anterior Eye. 2017 Apr;40(2):70-81
pubmed: 27884616
Eye Contact Lens. 2013 Jan;39(1):4-12
pubmed: 23292050
Invest Ophthalmol Vis Sci. 2013 Sep 11;54(9):6190-7
pubmed: 23942975
Arch Ophthalmol. 1967 Sep;78(3):328-30
pubmed: 6040008
Invest Ophthalmol Vis Sci. 2013 Oct 18;54(11):TFOS7-TFOS13
pubmed: 24058135
Optom Vis Sci. 2009 Aug;86(8):E1006-14
pubmed: 19584769
Cont Lens Anterior Eye. 2017 Oct;40(5):293-300
pubmed: 28550975
Cont Lens Anterior Eye. 2016 Aug;39(4):270-6
pubmed: 26818615
Adv Healthc Mater. 2015 Apr 22;4(6):792-810
pubmed: 25400274
PLoS One. 2019 May 14;14(5):e0216484
pubmed: 31086372
Eye Contact Lens. 2003 Jul;29(3):173-6
pubmed: 12861112
Cont Lens Anterior Eye. 2008 Apr;31(2):89-94
pubmed: 17964212
J Biomed Mater Res B Appl Biomater. 2013 Nov;101(8):1585-93
pubmed: 23559566
Biosens Bioelectron. 2011 Mar 15;26(7):3290-6
pubmed: 21257302
Biomaterials. 2010 May;31(14):4032-47
pubmed: 20153894
Invest Ophthalmol Vis Sci. 2018 Nov 1;59(14):DES56-DES63
pubmed: 30481807
J Biomed Mater Res B Appl Biomater. 2008 May;85(2):361-7
pubmed: 17957701
BMC Ophthalmol. 2018 Nov 3;18(1):286
pubmed: 30390645
Eye Contact Lens. 2010 Jan;36(1):2-5
pubmed: 20009942
Cont Lens Anterior Eye. 2004 Sep;27(3):133-48
pubmed: 16303536
Invest Ophthalmol Vis Sci. 2010 Apr;51(4):1911-7
pubmed: 19834035
Eye Contact Lens. 2010 Mar;36(2):73-6
pubmed: 20093938
Clin Exp Optom. 2018 Mar;101(2):188-192
pubmed: 29023989
Optom Vis Sci. 2014 Dec;91(12):1455-61
pubmed: 25303838