Myxoid neoplasms of bone and soft tissue: a pattern-based approach.


Journal

Journal of the American Society of Cytopathology
ISSN: 2213-2945
Titre abrégé: J Am Soc Cytopathol
Pays: United States
ID NLM: 101613234

Informations de publication

Date de publication:
Historique:
received: 17 07 2020
revised: 24 09 2020
accepted: 24 09 2020
pubmed: 11 11 2020
medline: 15 1 2022
entrez: 10 11 2020
Statut: ppublish

Résumé

The accurate diagnosis of musculoskeletal neoplasms is difficult but a pattern-based approach combined with ancillary testing has been shown to improve diagnostic accuracy. The pattern-based approach is particularly appropriate for myxoid lesions. The authors reviewed their personal experience of over 3 decades of diagnosing myxoid neoplasms of musculoskeletal lesions. The authors found that myxoid lesions can be accurately classified based on cell type, nuclear atypia, presence of blood vessel fragments, as well as the results of immunohistochemical and molecular testing. Musculoskeletal lesions with a prominence of myxoid or chondroid material in the background can be accurately diagnosed using pattern analysis and ancillary testing.

Identifiants

pubmed: 33168472
pii: S2213-2945(20)30314-8
doi: 10.1016/j.jasc.2020.09.009
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

278-292

Informations de copyright

Copyright © 2020 American Society of Cytopathology. Published by Elsevier Inc. All rights reserved.

Auteurs

Lester J Layfield (LJ)

Department of Pathology and Anatomical Sciences, University of Missouri, Columbia, Missouri. Electronic address: layfieldl@health.missouri.edu.

Leslie Dodd (L)

Department of Pathology and Laboratory Medicine, University of North Carolina, Chapel Hill, North Carolina.

Jerzy Klijanienko (J)

Department of Pathology, Curie Institute, Paris, France.

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Classifications MeSH