Characterization of glycosphingolipids from gastrointestinal stromal tumours.
Journal
Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288
Informations de publication
Date de publication:
09 11 2020
09 11 2020
Historique:
received:
02
03
2020
accepted:
23
10
2020
entrez:
10
11
2020
pubmed:
11
11
2020
medline:
12
3
2021
Statut:
epublish
Résumé
Gastrointestinal stromal tumours (GISTs) are the major nonepithelial neoplasms of the human gastrointestinal tract with a worldwide incidence between 11 and 15 per million cases annually. In this study the acid and non-acid glycosphingolipids of three GISTs were characterized using a combination of thin-layer chromatography, chemical staining, binding of carbohydrate recognizing ligands, and mass spectrometry. In the non-acid glycosphingolipid fractions of the tumors globotetraosylceramide, neolactotetraosylceramide, and glycosphingolipids with terminal blood group A, B, H, Le
Identifiants
pubmed: 33168837
doi: 10.1038/s41598-020-76104-3
pii: 10.1038/s41598-020-76104-3
pmc: PMC7653041
doi:
Substances chimiques
Glycosphingolipids
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
19371Références
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