Genetic association between the rs12252 SNP of the interferon-induced transmembrane protein gene and influenza A virus infection in the Korean population.
Case–control study
IFITM3
Single nucleotide polymorphism
rs12252 SNP
Journal
Molecular & cellular toxicology
ISSN: 1738-642X
Titre abrégé: Mol Cell Toxicol
Pays: Korea (South)
ID NLM: 101486570
Informations de publication
Date de publication:
2021
2021
Historique:
accepted:
21
10
2020
pubmed:
11
11
2020
medline:
11
11
2020
entrez:
10
11
2020
Statut:
ppublish
Résumé
Interferon-induced transmembrane protein 3 (IFITM3) is a potent host antiviral effector protein that blocks the invasion of various viruses, including the influenza A virus (IAV). The C allele of the rs12252 single nucleotide polymorphism (SNP) shows vulnerability to the pandemic 2009 H1N1 IAV in European and Asian populations. Here, we estimated the disease susceptibility of the rs12252 SNP with the pandemic 2009 H1N1 IAV infection in the Korean population. We carried out direct sequencing of the To the best of our knowledge, this was the first evaluation of the susceptibility of the pandemic 2009 H1N1 IAV in the Korean population.
Sections du résumé
BACKGROUND
BACKGROUND
Interferon-induced transmembrane protein 3 (IFITM3) is a potent host antiviral effector protein that blocks the invasion of various viruses, including the influenza A virus (IAV). The C allele of the rs12252 single nucleotide polymorphism (SNP) shows vulnerability to the pandemic 2009 H1N1 IAV in European and Asian populations.
OBJECTIVE
OBJECTIVE
Here, we estimated the disease susceptibility of the rs12252 SNP with the pandemic 2009 H1N1 IAV infection in the Korean population.
RESULTS
RESULTS
We carried out direct sequencing of the
CONCLUSION
CONCLUSIONS
To the best of our knowledge, this was the first evaluation of the susceptibility of the pandemic 2009 H1N1 IAV in the Korean population.
Identifiants
pubmed: 33169083
doi: 10.1007/s13273-020-00108-3
pii: 108
pmc: PMC7640581
doi:
Types de publication
Journal Article
Langues
eng
Pagination
51-57Informations de copyright
© The Korean Society of Toxicogenomics and Toxicoproteomics 2020 2020.
Déclaration de conflit d'intérêts
Conflict of interestThe authors declare no conflict of interest.
Références
Euro Surveill. 2010 Jan 14;15(2):
pubmed: 20085691
Nat Commun. 2013;4:1418
pubmed: 23361009
Intervirology. 2017;60(1-2):69-74
pubmed: 28813716
Euro Surveill. 2011 Sep 01;16(35):
pubmed: 21903041
J Virol. 2012 Dec;86(24):13697-707
pubmed: 23055554
PLoS Pathog. 2011 Oct;7(10):e1002337
pubmed: 22046135
J Infect Dis. 2017 Jul 1;216(1):97-104
pubmed: 28510725
PLoS Pathog. 2013 Jan;9(1):e1003124
pubmed: 23358889
Nat Med. 2017 Aug;23(8):975-983
pubmed: 28714988
Gene. 2018 Oct 20;674:70-79
pubmed: 29940276
Nat Rev Immunol. 2013 Jan;13(1):46-57
pubmed: 23237964
PLoS Pathog. 2012 Sep;8(9):e1002909
pubmed: 22969429
Nature. 2012 Mar 25;484(7395):519-23
pubmed: 22446628
J Infect Dis. 2014 Apr 1;209(7):1028-31
pubmed: 23997235
Tuberc Respir Dis (Seoul). 2016 Apr;79(2):70-3
pubmed: 27066083
Cell Mol Immunol. 2020 Jun;17(6):662-664
pubmed: 31685927
PLoS One. 2015 May 05;10(5):e0124985
pubmed: 25942469
Eur J Clin Microbiol Infect Dis. 2016 Nov;35(11):1811-1817
pubmed: 27492307
Immunogenetics. 2018 Mar;70(3):169-177
pubmed: 28842783
Cell. 2009 Dec 24;139(7):1243-54
pubmed: 20064371
J Virol. 2010 Dec;84(24):12646-57
pubmed: 20943977
Cell Microbiol. 2014 Jul;16(7):1080-93
pubmed: 24521078
J Infect Dis. 2018 Jan 4;217(2):257-262
pubmed: 29202190
Epidemiol Infect. 2015 Oct;143(14):2975-84
pubmed: 25778715
Epidemiol Infect. 2018 Nov 13;147:e39
pubmed: 30421689
Vet Res Commun. 2019 Nov;43(4):203-214
pubmed: 31410631