Using Anti-SARS-CoV-2 IgG and IgM Antibodies to Detect Outpatient Cases with Olfactory and Taste Disorders Suspected as Mild Form of COVID-19: a Retrospective Survey.

Anosmia COVID-19 IgG IgM Olfactory Taste

Journal

SN comprehensive clinical medicine
ISSN: 2523-8973
Titre abrégé: SN Compr Clin Med
Pays: Switzerland
ID NLM: 101740833

Informations de publication

Date de publication:
2020
Historique:
accepted: 27 10 2020
pubmed: 11 11 2020
medline: 11 11 2020
entrez: 10 11 2020
Statut: ppublish

Résumé

Many patients with olfactory disorders were referred during the COVID-19 pandemic in 2020. The aim of this study was to detect outpatient cases with olfactory and taste disorders suspected to mild form of COVID-19 disease in Gorgan city in the north of Iran retrospectively. This study was performed on patients who had the complaints of olfactory disorders during 03/01/2020 to 04/01/2020. They also had the mild symptoms of upper respiratory tract infection. The control group included patients who had similar symptoms during this period but did not report olfactory or taste disturbances. Due to the limitations of serologic kits, this study was performed 2-3 months after the onset of symptoms. The number of patients and controls was 72 and 36 respectively. The range and the mean ± SD of patient's age were 21-63 and 39.82 ± 9.82 years. In both groups, 44.44% were male and 55.56% were female. The time interval between the onset of symptoms and the serologic tests in both groups was 91.11 ± 16.20 days. In the cases and controls, the IgG titer was positive in 44.4% and 22.2% and the IgM titer was positive in 5.6% and 8.3% respectively. IgG antibody titers were higher in cases than in the control group (

Identifiants

pubmed: 33169109
doi: 10.1007/s42399-020-00623-3
pii: 623
pmc: PMC7608292
doi:

Types de publication

Journal Article

Langues

eng

Pagination

2554-2560

Informations de copyright

© Springer Nature Switzerland AG 2020.

Déclaration de conflit d'intérêts

Conflict of InterestThe authors declare that they have no conflict of interest.

Références

Physiol Behav. 1984 Mar;32(3):489-502
pubmed: 6463130
Acta Otorrinolaringol Esp. 2013 Sep-Oct;64(5):331-8
pubmed: 23948436
J Med Virol. 2020 Oct;92(10):2243-2247
pubmed: 32510168
Eur Arch Otorhinolaryngol. 2020 Aug;277(8):2251-2261
pubmed: 32253535
Clin Infect Dis. 2020 Jul 28;71(15):778-785
pubmed: 32198501
JAMA. 2002 Nov 13;288(18):2307-12
pubmed: 12425708
Med Hypotheses. 2020 Aug;141:109757
pubmed: 32344276
Int Forum Allergy Rhinol. 2020 Jul;10(7):806-813
pubmed: 32279441
Clin Infect Dis. 2020 Nov 5;71(8):1930-1934
pubmed: 32306047
Front Immunol. 2020 May 01;11:827
pubmed: 32425950
J Infect. 2020 Aug;81(2):e55-e58
pubmed: 32335168
PLoS Med. 2020 Oct 1;17(10):e1003358
pubmed: 33001967
Ecancermedicalscience. 2020 Apr 03;14:ed98
pubmed: 32269598
Acta Otolaryngol Suppl. 1998;538:191-6
pubmed: 9879419
Nat Med. 2020 Aug;26(8):1200-1204
pubmed: 32555424
Infect Chemother. 2020 Mar;52(1):110-112
pubmed: 32153144
Nat Med. 2020 Jun;26(6):845-848
pubmed: 32350462
Rhinology. 2020 Jun 1;58(3):295-298
pubmed: 32277751
Laryngoscope. 2020 Jul;130(7):1787
pubmed: 32237238
J Appl Lab Med. 2020 Sep 1;5(5):908-920
pubmed: 32428207
J Med Virol. 2021 Jan;93(1):97-98
pubmed: 32525558
Emerg Microbes Infect. 2020 Dec;9(1):940-948
pubmed: 32357808
Laryngoscope. 2020 Nov;130(11):2667-2673
pubmed: 32617990
Wien Klin Wochenschr. 2001 Jan 15;113(1-2):52-7
pubmed: 11233469
Otolaryngol Clin North Am. 2004 Dec;37(6):1159-66
pubmed: 15563908
SN Compr Clin Med. 2020 Jul 23;:1-5
pubmed: 32838175
Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2017 May 20;31(10):749-752
pubmed: 29771035
Infect Ecol Epidemiol. 2020 Apr 14;10(1):1754538
pubmed: 32363011
Arch Otolaryngol Head Neck Surg. 2009 Oct;135(10):1000-4
pubmed: 19841338
J Med Virol. 2020 Apr;92(4):424-432
pubmed: 31981224
Asian Pac J Allergy Immunol. 2020 Mar;38(1):1-9
pubmed: 32105090

Auteurs

Mohammad Hosein Taziki Balajelini (MH)

Department of Surgery, School of Medicine, Golestan University of Medical Sciences, Gorgan, Golestan Iran.

Mohammad Ali Vakili (MA)

Department of Family and Community Medicine, School of Medicine, Golestan University of Medical Sciences, Gorgan, Iran.

Mohsen Saeidi (M)

Department of Immunology, School of Medicine, Golestan University of Medical Sciences, Gorgan, Golestan Iran.

Alijan Tabarraei (A)

Department of Microbiology, School of Medicine, Infectious Diseases Research Center, Golestan University of Medical Sciences, Gorgan, Golestan Iran.

Seyed Mehran Hosseini (SM)

Department of Physiology, Neuroscience Research Center, School of Medicine, Golestan University of Medical Sciences, Shastkola, Gorgan, Golestan 4934174515 Iran.

Classifications MeSH