Long-term maintenance of virologic suppression in native and migrant HIV-1 naïve patients: an Italian cohort study.


Journal

AIDS care
ISSN: 1360-0451
Titre abrégé: AIDS Care
Pays: England
ID NLM: 8915313

Informations de publication

Date de publication:
09 2021
Historique:
pubmed: 12 11 2020
medline: 4 9 2021
entrez: 11 11 2020
Statut: ppublish

Résumé

Little is known about long-term maintenance of virologic suppression in HIV migrants in Italy. The study aims to compare virologic failure rates and associated factors among antiretroviral therapy (ART)-naïve migrants and natives enrolled in the ARCA database since 2007 who achieved virologic suppression within 18 months from the beginning of the ART. Kaplan-Meier method assessed the probability of virologic suppression and failure. Cox regression model was used for multivariate analysis. Of 2515 patients, 2020 (80.3%) were Italian, 286 (10.6%) migrants from low-income countries, of whom 201 (75.0%) from Africa, and 227 (9.0%) from high-income-countries. The median follow-up was 4.5 years (IQR 2.5-7). No difference was observed in the time of achievement of virological suppression in the three groups (log-rank:

Identifiants

pubmed: 33172289
doi: 10.1080/09540121.2020.1839011
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1159-1166

Auteurs

Filippo Lagi (F)

Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
Infectious and Tropical Diseases Unit, Careggi University and Hospital, Florence, Italy.

Seble Tekle Kiros (ST)

Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.

Simona Di Giambenedetto (S)

Institute of Clinical Infectious Diseases, Catholic University of Sacred Heart, Policlinico Gemelli, Rome, Italy.

Francesca Lombardi (F)

Institute of Clinical Infectious Diseases, Catholic University of Sacred Heart, Policlinico Gemelli, Rome, Italy.

Monica Pecorari (M)

Unit of Virology and Molecular Microbiology, University Hospital, Modena, Italy.

Vanni Borghi (V)

Department of Infectious Diseases, University of Modena, Modena, Italy.

Luciana Lepore (L)

Department of Biomedical Sciences and Human Oncology, Clinic of Infectious Diseases, University of Bari, Italy.

Laura Monno (L)

Department of Biomedical Sciences and Human Oncology, Clinic of Infectious Diseases, University of Bari, Italy.

Maurizio Setti (M)

Clinic of Immunology and Internal Medicine, Ospedale Policlinico San Martino, Genoa, Italy.

Valeria Micheli (V)

Microbiology and Virology Laboratory, L. Sacco Hospital, Milano, Italy.

Patrizia Bagnarelli (P)

Virology Unit, Azienda Ospedaliera Universitaria Ospedali Riuniti di Ancona, Ancona, Italy.

Elisabetta Paolini (E)

Immuno-Ematology and Transfusion Medicine Service, Cremona Hospital, Cremona, Italy.

Francesca Bai (F)

Infectious Diseases, San Paolo Hospital, Milan, Italy.

Alessandro Bartoloni (A)

Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
Infectious and Tropical Diseases Unit, Careggi University and Hospital, Florence, Italy.

Gaetana Sterrantino (G)

Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.

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Classifications MeSH