CD63

breast cancer cancer‐associated fibroblasts exosomes miR‐22 tamoxifen

Journal

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
ISSN: 2198-3844
Titre abrégé: Adv Sci (Weinh)
Pays: Germany
ID NLM: 101664569

Informations de publication

Date de publication:
Nov 2020
Historique:
received: 02 07 2020
entrez: 11 11 2020
pubmed: 12 11 2020
medline: 12 11 2020
Statut: epublish

Résumé

Tamoxifen remains the most effective treatment for estrogen receptor α (ERα)-positive breast cancer. However, many patients still develop resistance to tamoxifen in association with metastatic recurrence, which presents a tremendous clinical challenge. To better understand tamoxifen resistance from the perspective of the tumor microenvironment, the whole microenvironment landscape is charted by single-cell RNA sequencing and a new cancer-associated fibroblast (CAF) subset, CD63

Identifiants

pubmed: 33173749
doi: 10.1002/advs.202002518
pii: ADVS2025
pmc: PMC7610308
doi:

Types de publication

Journal Article

Langues

eng

Pagination

2002518

Informations de copyright

© 2020 The Authors. Published by Wiley‐VCH GmbH.

Déclaration de conflit d'intérêts

The authors declare no conflict of interest.

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Auteurs

Yuan Gao (Y)

The State Key Laboratory of Cancer Biology Biotechnology Center School of Pharmacy The Fourth Military Medical University Xi'an 710032 P. R. China.

Xiaoju Li (X)

The State Key Laboratory of Cancer Biology Biotechnology Center School of Pharmacy The Fourth Military Medical University Xi'an 710032 P. R. China.

Cheng Zeng (C)

The State Key Laboratory of Cancer Biology Biotechnology Center School of Pharmacy The Fourth Military Medical University Xi'an 710032 P. R. China.
Institute of Material Medical School of Pharmacy The Fourth Military Medical University Xi'an 710032 P. R. China.

Chenlin Liu (C)

The State Key Laboratory of Cancer Biology Biotechnology Center School of Pharmacy The Fourth Military Medical University Xi'an 710032 P. R. China.

Qiang Hao (Q)

The State Key Laboratory of Cancer Biology Biotechnology Center School of Pharmacy The Fourth Military Medical University Xi'an 710032 P. R. China.

Weina Li (W)

The State Key Laboratory of Cancer Biology Biotechnology Center School of Pharmacy The Fourth Military Medical University Xi'an 710032 P. R. China.

Kuo Zhang (K)

The State Key Laboratory of Cancer Biology Biotechnology Center School of Pharmacy The Fourth Military Medical University Xi'an 710032 P. R. China.

Wangqian Zhang (W)

The State Key Laboratory of Cancer Biology Biotechnology Center School of Pharmacy The Fourth Military Medical University Xi'an 710032 P. R. China.

Shuning Wang (S)

The State Key Laboratory of Cancer Biology Biotechnology Center School of Pharmacy The Fourth Military Medical University Xi'an 710032 P. R. China.

Huadong Zhao (H)

Department of General Surgery Tangdu Hospital The Fourth Military Medical University Xi'an 710038 P. R. China.

Dong Fan (D)

Department of General Surgery Tangdu Hospital The Fourth Military Medical University Xi'an 710038 P. R. China.

Meng Li (M)

The State Key Laboratory of Cancer Biology Biotechnology Center School of Pharmacy The Fourth Military Medical University Xi'an 710032 P. R. China.

Yingqi Zhang (Y)

The State Key Laboratory of Cancer Biology Biotechnology Center School of Pharmacy The Fourth Military Medical University Xi'an 710032 P. R. China.

Wei Zhang (W)

The State Key Laboratory of Cancer Biology Biotechnology Center School of Pharmacy The Fourth Military Medical University Xi'an 710032 P. R. China.

Cun Zhang (C)

The State Key Laboratory of Cancer Biology Biotechnology Center School of Pharmacy The Fourth Military Medical University Xi'an 710032 P. R. China.

Classifications MeSH