Informing the Risk of Kidney Transplantation Versus Remaining on the Waitlist in the Coronavirus Disease 2019 Era.
COVID-19
dialysis
immunosuppression
kidney transplantation
outcomes
transplant waitlist
Journal
Kidney international reports
ISSN: 2468-0249
Titre abrégé: Kidney Int Rep
Pays: United States
ID NLM: 101684752
Informations de publication
Date de publication:
Jan 2021
Jan 2021
Historique:
received:
07
09
2020
revised:
15
10
2020
accepted:
27
10
2020
pubmed:
12
11
2020
medline:
12
11
2020
entrez:
11
11
2020
Statut:
ppublish
Résumé
There are limited data pertaining to comparative outcomes of remaining on dialysis versus kidney transplantation as the threat of coronavirus disease 2019 (COVID-19) remains. In this study we delineate the differential risks involved using serologic methods to help define exposure rates. From a cohort of 1433 patients with end-stage kidney disease (ESKD), we analyzed COVID-19 infection rates and outcomes in 299 waitlist patients compared with 237 transplant recipients within their first year post-transplant. Patients were followed over a 68-day period from the time our transplant program closed due to COVID-19. The overall mortality rates in waitlist and transplant populations were equivalent ( Although COVID-19 infection was more common in the waitlist patients, a higher COVID-19‒associated mortality rate was seen in the transplant recipients, resulting in comparable overall mortality rates.
Identifiants
pubmed: 33173838
doi: 10.1016/j.ekir.2020.10.032
pii: S2468-0249(20)31703-4
pmc: PMC7644242
doi:
Types de publication
Journal Article
Langues
eng
Pagination
46-55Investigateurs
Maura Appelbe
(M)
Edwina Brown
(E)
Tom Cairns
(T)
Caroline Clerkin
(C)
Marie Condon
(M)
Richard W Corbett
(RW)
Jeremy Crane
(J)
Frank Dor
(F)
Neill Duncan
(N)
Claire Edwards
(C)
Fabiana Fernandes da Costa
(F)
Andrew Frankel
(A)
Dawn Goodall
(D)
Julie Harris
(J)
Sharon Harris
(S)
Paul Herbert
(P)
Peter Hill
(P)
Andreas Kousios
(A)
Jeremy B Levy
(JB)
Lian Liu
(L)
Marina Loucaidou
(M)
Kathleen Lynch
(K)
Nicholas Medjeral-Thomas
(N)
Dihlabelo Moabi
(D)
Anand Muthusamy
(A)
Margaret Nevin
(M)
Andrew Palmer
(A)
Darren Parsons
(D)
Virginia Prout
(V)
Sue Punzalan
(S)
Emma Salisbury
(E)
Eleanor Sandhu
(E)
Colin Smith
(C)
Roland Storey
(R)
Anisha Tanna
(A)
Katie Tansey
(K)
David Thomas
(D)
James Tomlinson
(J)
Vassilios Papalois
(V)
Phil Webster
(P)
Dejing Yang
(D)
Commentaires et corrections
Type : CommentIn
Informations de copyright
© 2020 Published by Elsevier, Inc., on behalf of the International Society of Nephrology.
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