Two clusters of Toscana virus meningo-encephalitis in Livorno Province and Elba Island, July-September 2018.
Adult
Antibodies, Viral
/ blood
Communicable Diseases, Emerging
/ epidemiology
Disease Outbreaks
Female
Follow-Up Studies
Humans
Immunoglobulin G
/ blood
Immunoglobulin M
/ blood
Interviews as Topic
Italy
/ epidemiology
Male
Mediterranean Islands
/ epidemiology
Meningitis, Aseptic
/ diagnosis
Meningoencephalitis
/ diagnosis
Middle Aged
Occupational Diseases
/ epidemiology
Phlebotomus Fever
/ diagnosis
Sandfly fever Naples virus
/ immunology
Seasons
Surveys and Questionnaires
Tourism
Travel-Related Illness
Young Adult
Italy
Outbreak
Toscana virus
Vector-borne disease
Journal
Annali di igiene : medicina preventiva e di comunita
ISSN: 1120-9135
Titre abrégé: Ann Ig
Pays: Italy
ID NLM: 9002865
Informations de publication
Date de publication:
Historique:
entrez:
11
11
2020
pubmed:
12
11
2020
medline:
21
10
2021
Statut:
ppublish
Résumé
Toscana virus (TOSV) is an arbovirus transmitted to humans by Phlebotomus spp sandflies. It causes aseptic meningitis and meningoencephalitis with marked seasonality. Here we describe the clinical, microbiological and epidemiological features of two clusters of cases occurred in Tuscany in 2018. A confirmed case was defined as the detection of anti-TOSV IgM and IgG in serum sample, in presence of typical clinical manifestations. We consulted hospital records of hospitalized patients to collect clinical information and obtained epidemiological information from the local health authority investigation report. We telephonically interviewed patients using a standard questionnaire for a 6 months follow-up. A total of 12 cases of TOSV meningo-encephalitis with onset between 4th of July and 12th of September accessed health care services in the province of Livorno. Eight cases were males with median age 41,5 and four were not resident in the area. Serological investigations confirmed a recent TOSV infection. Eight cases reported visiting Elba Island and four had a possible occupational-related exposure. This surge of infection emphasizes the need of information campaigns coupled with adequate surveillance and control interventions against TOSV that, among other arboviruses, is a growing issue of concern in Italy.
Sections du résumé
BACKGROUND
Toscana virus (TOSV) is an arbovirus transmitted to humans by Phlebotomus spp sandflies. It causes aseptic meningitis and meningoencephalitis with marked seasonality. Here we describe the clinical, microbiological and epidemiological features of two clusters of cases occurred in Tuscany in 2018.
METHODS
A confirmed case was defined as the detection of anti-TOSV IgM and IgG in serum sample, in presence of typical clinical manifestations. We consulted hospital records of hospitalized patients to collect clinical information and obtained epidemiological information from the local health authority investigation report. We telephonically interviewed patients using a standard questionnaire for a 6 months follow-up.
RESULTS
A total of 12 cases of TOSV meningo-encephalitis with onset between 4th of July and 12th of September accessed health care services in the province of Livorno. Eight cases were males with median age 41,5 and four were not resident in the area. Serological investigations confirmed a recent TOSV infection. Eight cases reported visiting Elba Island and four had a possible occupational-related exposure.
CONCLUSIONS
This surge of infection emphasizes the need of information campaigns coupled with adequate surveillance and control interventions against TOSV that, among other arboviruses, is a growing issue of concern in Italy.
Identifiants
pubmed: 33175077
doi: 10.7416/ai.2020.2387
doi:
Substances chimiques
Antibodies, Viral
0
Immunoglobulin G
0
Immunoglobulin M
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM