The value of 3D-real IR MRI with intravenous gadolinium injection in the diagnosis of suspected Meniere's disease in children.
Adolescent
Audiometry
Child
Contrast Media
/ administration & dosage
Ear, Inner
/ diagnostic imaging
Endolymphatic Hydrops
/ diagnostic imaging
Female
Gadolinium DTPA
/ administration & dosage
Humans
Imaging, Three-Dimensional
Injections, Intravenous
Magnetic Resonance Imaging
/ methods
Male
Meniere Disease
/ diagnostic imaging
Perilymph
320.41
3D-real IR
Meniere’s disease
Suspected diagnosis
children
intravenous gadolinium injection
Journal
Acta oto-laryngologica
ISSN: 1651-2251
Titre abrégé: Acta Otolaryngol
Pays: England
ID NLM: 0370354
Informations de publication
Date de publication:
Feb 2021
Feb 2021
Historique:
pubmed:
13
11
2020
medline:
21
10
2021
entrez:
12
11
2020
Statut:
ppublish
Résumé
Intravenous gadolinium injection (IV-method) can be used to visualize endolymphatic hydrops. This study was designed to use a three-dimensional inversion-recovery sequence with real reconstruction (3 D-real IR) sequence 4 h after the IV-method, images of the perilymph space were scored for endolymphatic hydrops in cases of suspected Meniere's disease (MD) in children to investigate its diagnostic value of MD in children. We collected 28 suspected MD children aged ≤17 years old, all of whom underwent the IV-method. After 4 h, inner ear 3 D-real IR magnetic resonance imaging (MRI) was performed and results were analyzed. Gadolinium contrast agent was seen distributed in the perilymphatic space with perilymphatic enhancement on 3 D-real IR MRI, allowing differentiation between the perilymphatic and endolymphatic spaces. Based on perilymph MRI diagnostic scoring, 64.3% (18/28) of the patients were categorized as having endolymphatic hydrops, who were followed and eventually diagnosed with confirmed MDs. Suspected MD children should undergo gadolinium-enhanced examinations of the inner ear while taking dynamic audiology examinations for the confirmed diagnosis.
Sections du résumé
BACKGROUND
BACKGROUND
Intravenous gadolinium injection (IV-method) can be used to visualize endolymphatic hydrops.
AIMS/OBJECTIVES
OBJECTIVE
This study was designed to use a three-dimensional inversion-recovery sequence with real reconstruction (3 D-real IR) sequence 4 h after the IV-method, images of the perilymph space were scored for endolymphatic hydrops in cases of suspected Meniere's disease (MD) in children to investigate its diagnostic value of MD in children.
MATERIALS AND METHODS
METHODS
We collected 28 suspected MD children aged ≤17 years old, all of whom underwent the IV-method. After 4 h, inner ear 3 D-real IR magnetic resonance imaging (MRI) was performed and results were analyzed.
RESULTS
RESULTS
Gadolinium contrast agent was seen distributed in the perilymphatic space with perilymphatic enhancement on 3 D-real IR MRI, allowing differentiation between the perilymphatic and endolymphatic spaces. Based on perilymph MRI diagnostic scoring, 64.3% (18/28) of the patients were categorized as having endolymphatic hydrops, who were followed and eventually diagnosed with confirmed MDs.
CONCLUSIONS AND SIGNIFICANCE
CONCLUSIONS
Suspected MD children should undergo gadolinium-enhanced examinations of the inner ear while taking dynamic audiology examinations for the confirmed diagnosis.
Identifiants
pubmed: 33176531
doi: 10.1080/00016489.2020.1843071
doi:
Substances chimiques
Contrast Media
0
Gadolinium DTPA
K2I13DR72L
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM