Global, regional, and national burdens of bladder cancer in 2017: estimates from the 2017 global burden of disease study.


Journal

BMC public health
ISSN: 1471-2458
Titre abrégé: BMC Public Health
Pays: England
ID NLM: 100968562

Informations de publication

Date de publication:
11 Nov 2020
Historique:
received: 22 06 2020
accepted: 04 11 2020
entrez: 12 11 2020
pubmed: 13 11 2020
medline: 15 5 2021
Statut: epublish

Résumé

The aim of this study is to describe the prevalence and mortality of bladder cancer (BCa) using data obtained in the Global Burden of Disease study performed in 2017 (GBD 2017). Data on BCa for 2017, including prevalence, mortality, and disability-adjusted life years (DALYs), were obtained from GBD 2017 at the global, regional, and national levels. We also analyzed the association of BCa burden with the country development level. There were 2.63 million BCa cases estimated from the GBD 2017 data, with 200,000 persons dying of BCa, resulting in 3.60 million DALYs in 2017. The age-standardized prevalence (ASP) of BCa was 32.91/100,000 persons, and age-standardized death rate (ASDR) was 2.57/100,000 persons. The ASP and ASDR of BCa were higher in males than in females, and higher in people older than 60 years. The ASP and ASDR of BCa were higher in Western Europe and Central Europe than in South Asia, Andean Latin America, and Central Latin America, and higher in countries with a higher sociodemographic index (SDI). Correlation analysis identified that the ASP and ASDR of BCa were positively correlated with the country SDI (P < 0.0001 and ρ = 0.68 for ASP, and P = 0.0048 and ρ = 0.20 for ASDR). In addition, 33.72% deaths and 36.80% DALYs caused by BCa could be attributed to smoking globally. The prevalence and mortality of BCa were very high in 2017, especially in high-SDI countries. Smoking-cessation strategies should be strengthened to control the burden associated with BCa.

Sections du résumé

BACKGROUND BACKGROUND
The aim of this study is to describe the prevalence and mortality of bladder cancer (BCa) using data obtained in the Global Burden of Disease study performed in 2017 (GBD 2017).
METHODS METHODS
Data on BCa for 2017, including prevalence, mortality, and disability-adjusted life years (DALYs), were obtained from GBD 2017 at the global, regional, and national levels. We also analyzed the association of BCa burden with the country development level.
RESULTS RESULTS
There were 2.63 million BCa cases estimated from the GBD 2017 data, with 200,000 persons dying of BCa, resulting in 3.60 million DALYs in 2017. The age-standardized prevalence (ASP) of BCa was 32.91/100,000 persons, and age-standardized death rate (ASDR) was 2.57/100,000 persons. The ASP and ASDR of BCa were higher in males than in females, and higher in people older than 60 years. The ASP and ASDR of BCa were higher in Western Europe and Central Europe than in South Asia, Andean Latin America, and Central Latin America, and higher in countries with a higher sociodemographic index (SDI). Correlation analysis identified that the ASP and ASDR of BCa were positively correlated with the country SDI (P < 0.0001 and ρ = 0.68 for ASP, and P = 0.0048 and ρ = 0.20 for ASDR). In addition, 33.72% deaths and 36.80% DALYs caused by BCa could be attributed to smoking globally.
CONCLUSION CONCLUSIONS
The prevalence and mortality of BCa were very high in 2017, especially in high-SDI countries. Smoking-cessation strategies should be strengthened to control the burden associated with BCa.

Identifiants

pubmed: 33176751
doi: 10.1186/s12889-020-09835-7
pii: 10.1186/s12889-020-09835-7
pmc: PMC7659112
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1693

Subventions

Organisme : the National Social Science Foundation of China
ID : 16BGL183
Organisme : Science and Technology Development of Shaanxi Province, China
ID : 2019SF-140

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Auteurs

Hairong He (H)

Clinical Research Center, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, Shaanxi, China.
School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, China.

Hongjun Xie (H)

Department of Urology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.

Yule Chen (Y)

Department of Urology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.

Chengzhuo Li (C)

School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, China.

Didi Han (D)

School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, China.

Fengshuo Xu (F)

School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, China.

Jun Lyu (J)

Clinical Research Center, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, Shaanxi, China. lyujun2020@jnu.edu.cn.
School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, China. lyujun2020@jnu.edu.cn.
Department of Clinical Research, The First Affiliated Hospital of Jinan University, Guangzhou, China. lyujun2020@jnu.edu.cn.

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