Conformal Coating of Orthopedic Plates with X-ray Scintillators and pH Indicators for X-ray Excited Luminescence Chemical Imaging through Tissue.
Animals
Biocompatible Materials
/ chemistry
Biofilms
/ drug effects
Cell Line
Cell Survival
/ drug effects
Epoxy Compounds
/ chemistry
Gadolinium
/ chemistry
Hydrogels
/ chemistry
Hydrogen-Ion Concentration
Luminescent Agents
/ chemistry
Mice
Polyethylene Glycols
/ chemistry
Prostheses and Implants
Rabbits
Stainless Steel
/ chemistry
Staphylococcus aureus
/ physiology
Tibia
/ diagnostic imaging
Titanium
/ chemistry
Ultraviolet Rays
X-ray scintillators
XELCI
bioimaging
epoxy coating
implant-associated infection
orthopedic coatings
pH indicators
pH sensing
Journal
ACS applied materials & interfaces
ISSN: 1944-8252
Titre abrégé: ACS Appl Mater Interfaces
Pays: United States
ID NLM: 101504991
Informations de publication
Date de publication:
25 Nov 2020
25 Nov 2020
Historique:
pubmed:
13
11
2020
medline:
26
2
2021
entrez:
12
11
2020
Statut:
ppublish
Résumé
We describe a pH-indicating material that can be directly implanted or coated on orthopedic implant surfaces to provide high-spatial-resolution pH mapping through tissue by X-ray excited luminescence chemical imaging (XELCI). This is especially useful for detecting local pH changes during treatment of implant-associated infections. The material has two layers: an X-ray scintillator layer with Gd
Identifiants
pubmed: 33181017
doi: 10.1021/acsami.0c13707
doi:
Substances chimiques
Biocompatible Materials
0
Epoxy Compounds
0
Hydrogels
0
Luminescent Agents
0
Stainless Steel
12597-68-1
Polyethylene Glycols
3WJQ0SDW1A
Gadolinium
AU0V1LM3JT
Titanium
D1JT611TNE
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM