IMMUNOGLOBULIN G4-RELATED OPHTHALMIC DISEASE MIMICKING INTRAOCULAR LYMPHOMA: A CASE REPORT.
Journal
Retinal cases & brief reports
ISSN: 1937-1578
Titre abrégé: Retin Cases Brief Rep
Pays: United States
ID NLM: 101298744
Informations de publication
Date de publication:
01 Jan 2022
01 Jan 2022
Historique:
pubmed:
13
11
2020
medline:
28
12
2021
entrez:
12
11
2020
Statut:
ppublish
Résumé
To describe a case of immunoglobulin G4-related choroiditis mimicking intraocular lymphoma. The patient underwent a complete ophthalmological evaluation including multimodal imaging, with structural optical coherence tomography, fluorescein angiography, indocyanine green angiography, ultra-widefield color, and autofluorescent fundus photographies to assess the ocular involvement. Patient's best-corrected visual acuity was of 20/25 in the right eye and 20/20 in the left eye. Fundus appearance showed abnormal yellowish choroidal lesions and moderate vitritis in both eyes. Fluorescein angiography was within normal limits, whereas indocyanine green angiography showed areas of choroiditis in both eyes, and structural optical coherence tomography scans disclosed retinal small roundish lesions in the corresponding regions. Laboratory examinations and lymph node biopsy led to the final diagnosis of immunoglobulin G4-related disease. We describe a case of immunoglobulin G4-related choroiditis mimicking intraocular lymphoma. The proper use of multimodal imaging associated with laboratory investigations was helpful to reach the correct diagnosis.
Identifiants
pubmed: 33181803
pii: 01271216-202201000-00009
doi: 10.1097/ICB.0000000000001087
doi:
Types de publication
Case Reports
Langues
eng
Sous-ensembles de citation
IM
Pagination
32-35Références
Hamano H, Kawa S, Horiuchi A, et al. High serum IgG4 concentrations in patients with sclerosing pancreatitis. N Engl J Med 2001;344:732–738.
Derzko-Dzulynsky L. IgG4-related disease in the eye and ocular adnexa. Curr Opin Ophthalmol 2017;28:617–622.
Wu N, Sun FY. Clinical observation of orbital IgG4-related diseases. Exp Ther Med 2019;17:883–887.
Cheuk W, Yuen HK, Chan JK. Chronic sclerosing dacryoadenitis: part of the spectrum of IgG4-related sclerosing disease? Am J Surg Pathol 2007;31:643–645.
Takahira M, Kawano M, Zen Y, et al. IgG4-Related chronic sclerosing dacryoadenitis. Arch Ophthalmol 2007;125:1575–1578.
Wallace ZS, Naden RP, Chari S, et al. The 2019 American College of Rheumatology/European League against rheumatism classification criteria for IgG4-related disease. Arthritis Reumatol 2020;72:7–19.
Umehara H, Okazaki K, Nakamura T, et al. Current approach to the diagnosis of IgG4-related disease: combination of comprehensive diagnostic and organ-specific criteria [review article]. Mod Rheumatol 2017;27:381–391.
Prayson R. Immunoglobulin G4-related ophthalmic disease presenting as uveitis. J Clin Neurosci 2015;22:1848–1849.
Gange WS, Holland SM, De Alba F. IgG4-related ophthalmic disease presenting as choroidal and orbital lesions. Retin Cases Brief Rep 2019;13:283–286.
Sogabe Y, Ohshima K, Azumi A, et al. Location and frequency of lesions in patients with IgG4-related ophthalmic diseases. Graefes Arch Clin Exp Ophthalmol 2014;252:531–538.
Mavrommatis MA, Avila SA, France R. IgG4-Related ophthalmic disease presenting as meningitis and panuveitis. Case Rep Ophthalmol Med 2019;2019:5653282.
Tsui E, Goldberg NR, Pillai C, et al. Multimodal imaging of IgG4-related papillitis and retinal disease. Retin Cases Brief Rep 2019. doi: 10.1097/ICB.0000000000000902. Epub ahead of print.
doi: 10.1097/ICB.0000000000000902
Wick MR, O'Malley DP. Lymphadenopathy associated with IgG4-related disease: diagnosis and differential diagnosis. Semin Diagn Pathol 2018;35:61–66.
Koenigstein D, Neudorfer M, Goldenberg D, et al. Choroidal effusion as an ocular manifestation of immunoglobulin G4-related disease. Retin Cases Brief Rep 2016;10:197–200.
Goto H, Takahira M, Azumi A. Diagnostic criteria for IgG4-related ophthalmic disease. Jpn J Ophthalmol 2014;59:1–7.
Mulay K, Honavar SG. Orbital immunoglobulin G4-related disease: a systematic review. Asia Pac J Ophthalmol 2014;3:322–325.
Savino G, Campana A, Petrone G, et al. In search of a disease. Surv Ophthalmol 2017;62:716–721.
Wallace Z, Deshpande V, Stone JH. Ophthalmic manifestations of IgG4-related disease: single center experience and literature review. Semin Arthritis Rheum 2014;43:806–817.
Khosroshahi A, Stone JH. Treatment approaches to IgG4-related systemic disease. Curr Opin Rheumatol 2011;23:67–71.
Khosroshahi A, Carruthers MN, Deshpande V, et al. Rituximab for the treatment of IgG4-related disease: lessons from 10 consecutive patients. Med (Baltimore) 2012;91:57–66.
Miserocchi E, Pontikaki I, Modorati G, et al. Anti-CD 20 monoclonal antibody (rituximab) treatment for inflammatory ocular diseases. Autoimmun Rev 2011;11:35–39.
Cicinelli MV, Marchese A, Miserocchi E, et al. Retinal and choroidal changes of vitreoretinal lymphoma from active to remission phase after intravitreal rituximab. Ocul Immunol Inflamm 2019;8:1–10.
Topazian M, Witzig TE, Smyrk TC, et al. Rituximab therapy for refractory biliary strictures in immunoglobulin G4-associated cholangitis. Clin Gastroenterol Hepatol 2008;6:364–366.