Biomimetic Alginate/Gelatin Cross-Linked Hydrogels Supplemented with Polyphosphate for Wound Healing Applications.
Alginates
/ chemistry
Biocompatible Materials
/ chemistry
Biomimetics
Cell Movement
Cell Survival
Epidermis
/ metabolism
Extracellular Matrix
/ chemistry
Gelatin
/ chemistry
Humans
Hydrogels
/ chemistry
Hydrogen-Ion Concentration
Ions
Keratinocytes
/ cytology
Metal Nanoparticles
/ chemistry
Nanoparticles
/ chemistry
Polyphosphates
/ chemistry
Porosity
Skin
/ radiation effects
Spectroscopy, Fourier Transform Infrared
Tissue Engineering
Tissue Scaffolds
/ chemistry
Wound Healing
Zinc
/ chemistry
alginate
cell migration
coacervate
gelatin
human epidermal keratinocytes
inorganic polyphosphate
ionic cross-linking
nanoparticles
periodate oxidation
zinc ions
Journal
Molecules (Basel, Switzerland)
ISSN: 1420-3049
Titre abrégé: Molecules
Pays: Switzerland
ID NLM: 100964009
Informations de publication
Date de publication:
09 Nov 2020
09 Nov 2020
Historique:
received:
20
09
2020
revised:
27
10
2020
accepted:
06
11
2020
entrez:
13
11
2020
pubmed:
14
11
2020
medline:
22
4
2021
Statut:
epublish
Résumé
In the present study, the fabrication of a biomimetic wound dressing that mimics the extracellular matrix, consisting of a hydrogel matrix composed of non-oxidized and periodate-oxidized marine alginate, was prepared to which gelatin was bound via Schiff base formation. Into this alginate/oxidized-alginate-gelatin hydrogel, polyP was stably but reversibly integrated by ionic cross-linking with Zn
Identifiants
pubmed: 33182366
pii: molecules25215210
doi: 10.3390/molecules25215210
pmc: PMC7664853
pii:
doi:
Substances chimiques
Alginates
0
Biocompatible Materials
0
Hydrogels
0
Ions
0
Polyphosphates
0
Gelatin
9000-70-8
Zinc
J41CSQ7QDS
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Bundesministerium für Forschung und Technologie
ID : 13GW0403B
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