Surface-Enhanced Raman Scattering-Based Lateral-Flow Immunoassay.
immunochromatography
lateral flow immunoassay
surface-enhanced Raman scattering
tags
Journal
Nanomaterials (Basel, Switzerland)
ISSN: 2079-4991
Titre abrégé: Nanomaterials (Basel)
Pays: Switzerland
ID NLM: 101610216
Informations de publication
Date de publication:
10 Nov 2020
10 Nov 2020
Historique:
received:
15
10
2020
revised:
06
11
2020
accepted:
07
11
2020
entrez:
13
11
2020
pubmed:
14
11
2020
medline:
14
11
2020
Statut:
epublish
Résumé
Lateral flow immunoassays (LFIAs) have been developed and used in a wide range of applications, in point-of-care disease diagnoses, environmental safety, and food control. However, in its classical version, it has low sensitivity and can only perform semiquantitative detection, based on colorimetric signals. Over the past decade, surface-enhanced Raman scattering (SERS) tags have been developed in order to decrease the detection limit and enable the quantitative analysis of analytes. Of note, these tags needed new readout systems and signal processing algorithms, while the LFIA design remained unchanged. This review highlights SERS strategies of signal enhancement for LFIAs. The types of labels used, the possible gain in sensitivity from their use, methods of reading and processing the signal, and the prospects for use are discussed.
Identifiants
pubmed: 33182579
pii: nano10112228
doi: 10.3390/nano10112228
pmc: PMC7696391
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Subventions
Organisme : Russian Foundation for Basic Research
ID : 18-52-7803
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