COVID-19 and Comorbidities: Is Inflammation the Underlying Condition in Children? A Narrative Review.
COVID-19
children
coronavirus
inflammation
pathogenic
risk factors
Journal
Current pediatric reviews
ISSN: 1875-6336
Titre abrégé: Curr Pediatr Rev
Pays: United Arab Emirates
ID NLM: 101240290
Informations de publication
Date de publication:
2021
2021
Historique:
received:
14
05
2020
revised:
06
10
2020
accepted:
08
10
2020
pubmed:
14
11
2020
medline:
17
4
2021
entrez:
13
11
2020
Statut:
ppublish
Résumé
This paper examines the potential link between COVID-19 and the presence of comorbidities and assesses the role of inflammation in this correlation. In COVID-19 patients, the most frequently associated diseases share a pathogenic inflammatory basis and apparently act as a risk factor in the onset of a more severe form of the disease, particularly in adulthood. However, in children, the understanding of the underlying pathogenic mechanisms is often complicated by the milder symptoms presented. A series of theories have, therefore, been put forward with a view of providing a better understanding of the role played by inflammation in this dramatic setting. All evidence available to date on this topic is discussed in this review.
Identifiants
pubmed: 33183207
pii: CPR-EPUB-111442
doi: 10.2174/1573396316666201112093920
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
38-44Informations de copyright
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