Clinical screening and identification of sarcopenic obesity in adults with advanced knee osteoarthritis.
Body composition
Grip strength
Obesity
Osteoarthritis
Sarcopenia
Screening
Journal
Clinical nutrition ESPEN
ISSN: 2405-4577
Titre abrégé: Clin Nutr ESPEN
Pays: England
ID NLM: 101654592
Informations de publication
Date de publication:
12 2020
12 2020
Historique:
received:
08
03
2020
revised:
17
07
2020
accepted:
14
08
2020
entrez:
13
11
2020
pubmed:
14
11
2020
medline:
25
9
2021
Statut:
ppublish
Résumé
Sarcopenic obesity (defined as low muscle mass and strength with high adiposity) requires attention in adults with advanced knee osteoarthritis (OA) due to implications on treatment outcomes. This study aimed to identify muscle function measures and patient characteristics associated with the presence of low muscle mass that could be used to screen and detect sarcopenic obesity in patients with knee OA in the clinical setting. Cross-sectional study of patients with knee OA and a body mass index (BMI) ≥30 kg/m Sex and relative grip strength were associated with low muscle mass (AUC 0.774, p < 0.001). Cut-points for low relative grip strength (<0.65 kg/m Relative grip strength shows promise as a clinical screening measure for sarcopenic obesity in patients with knee OA.
Sections du résumé
BACKGROUND AND AIMS
Sarcopenic obesity (defined as low muscle mass and strength with high adiposity) requires attention in adults with advanced knee osteoarthritis (OA) due to implications on treatment outcomes. This study aimed to identify muscle function measures and patient characteristics associated with the presence of low muscle mass that could be used to screen and detect sarcopenic obesity in patients with knee OA in the clinical setting.
METHODS
Cross-sectional study of patients with knee OA and a body mass index (BMI) ≥30 kg/m
RESULTS
Sex and relative grip strength were associated with low muscle mass (AUC 0.774, p < 0.001). Cut-points for low relative grip strength (<0.65 kg/m
CONCLUSION
Relative grip strength shows promise as a clinical screening measure for sarcopenic obesity in patients with knee OA.
Identifiants
pubmed: 33183561
pii: S2405-4577(20)30174-1
doi: 10.1016/j.clnesp.2020.08.005
pii:
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
340-348Informations de copyright
Copyright © 2020 European Society for Clinical Nutrition and Metabolism. Published by Elsevier Ltd. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of Competing Interest All authors declare no competing interests that would create a conflict of interest in connection with this manuscript. KG, CMP and MF have no disclosures. LJW has received consulting fees from Eli Lily and Scholar Rock for research not related to this study.