Paratonia in Dementia: A Systematic Review.
Dementia
motor disorders
motor skills disorders
paratonia
systematic review
Journal
Journal of Alzheimer's disease : JAD
ISSN: 1875-8908
Titre abrégé: J Alzheimers Dis
Pays: Netherlands
ID NLM: 9814863
Informations de publication
Date de publication:
2020
2020
Historique:
pubmed:
14
11
2020
medline:
30
9
2021
entrez:
13
11
2020
Statut:
ppublish
Résumé
Paratonia is a dementia-induced motor abnormality. Although paratonia affects virtually all people with dementia, it is not well known among clinicians and researchers. The aim of this study was to perform a systematic review of the literature on the definition, pathogenesis, diagnosis, and intervention of paratonia as well as to propose a research agenda for paratonia. In this systematic review, the Embase, PubMed, CINAHL, and Cochrane CENTRAL databases were searched for articles published prior to December 2019. Two independent reviewers performed data extraction and assessed the risk of bias of the studies. The following data were extracted: first author, year of publication, study design, study population, diagnosis, assessment, pathogenesis, therapy and interventions. Thirty-five studies met the inclusion criteria and were included. Most studies included in the review mention clinical criteria for paratonia. Additionally, pathogenesis, method of assessment, diagnosis, and paratonia severity as are interventions to address paratonia are also discussed. This systematic review outlines what is currently known about paratonia, as well as discusses the preliminary research on the underlying mechanisms of paratonia. Although paratonia has obvious devastating impacts on health and quality of life, the amount of research to date has been limited. In the last decade, there appears to have been increased research on paratonia, which hopefully will increase the momentum to further advance the field.
Sections du résumé
BACKGROUND
Paratonia is a dementia-induced motor abnormality. Although paratonia affects virtually all people with dementia, it is not well known among clinicians and researchers.
OBJECTIVE
The aim of this study was to perform a systematic review of the literature on the definition, pathogenesis, diagnosis, and intervention of paratonia as well as to propose a research agenda for paratonia.
METHODS
In this systematic review, the Embase, PubMed, CINAHL, and Cochrane CENTRAL databases were searched for articles published prior to December 2019. Two independent reviewers performed data extraction and assessed the risk of bias of the studies. The following data were extracted: first author, year of publication, study design, study population, diagnosis, assessment, pathogenesis, therapy and interventions.
RESULTS
Thirty-five studies met the inclusion criteria and were included. Most studies included in the review mention clinical criteria for paratonia. Additionally, pathogenesis, method of assessment, diagnosis, and paratonia severity as are interventions to address paratonia are also discussed.
CONCLUSION
This systematic review outlines what is currently known about paratonia, as well as discusses the preliminary research on the underlying mechanisms of paratonia. Although paratonia has obvious devastating impacts on health and quality of life, the amount of research to date has been limited. In the last decade, there appears to have been increased research on paratonia, which hopefully will increase the momentum to further advance the field.
Identifiants
pubmed: 33185600
pii: JAD200691
doi: 10.3233/JAD-200691
pmc: PMC7836054
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Systematic Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
1615-1637Références
J Neurol Neurosurg Psychiatry. 1977 Oct;40(10):956-66
pubmed: 591973
PLoS One. 2014 Dec 23;9(12):e114733
pubmed: 25536218
Arch Neurol. 2010 Aug;67(8):980-6
pubmed: 20697049
BMC Geriatr. 2007 Dec 19;7:30
pubmed: 18093298
J Am Med Dir Assoc. 2019 Dec;20(12):1521-1528
pubmed: 31227470
Arq Neuropsiquiatr. 2005 Sep;63(3A):577-82
pubmed: 16172703
Protein Pept Lett. 2008;15(4):385-91
pubmed: 18473952
Int Psychogeriatr. 2011 Sep;23(7):1051-60
pubmed: 21269542
J Am Geriatr Soc. 2002 Dec;50(12):1969-77
pubmed: 12473008
Can Med Assoc J. 1974 Jan 19;110(2):147-53
pubmed: 4810188
J Gerontol A Biol Sci Med Sci. 2017 May 1;72(5):655-661
pubmed: 27302701
Handb Clin Neurol. 2007;83:329-42
pubmed: 18808920
Am J Geriatr Psychiatry. 2007 Apr;15(4):351-3
pubmed: 17384318
Exp Brain Res. 2017 Mar;235(3):949-956
pubmed: 27999892
Brain Inj. 2013;27(10):1093-105
pubmed: 23885710
J Geriatr Phys Ther. 2006;29(2):50-6
pubmed: 16914066
BMC Med Inform Decis Mak. 2007 Jun 15;7:16
pubmed: 17573961
J Gerontol A Biol Sci Med Sci. 2018 Oct 8;73(11):1545-1551
pubmed: 29718128
Monatsschr Psychiatr Neurol. 1949 Nov;118(5):257-72
pubmed: 15395792
Neurology. 1998 Oct;51(4):968-71
pubmed: 9781514
Acta Neurol Scand. 1989 Jul;80(1):64-7
pubmed: 2782043
BMJ. 2015 Jan 02;350:g7647
pubmed: 25555855
Arch Neurol. 1990 Dec;47(12):1318-23
pubmed: 2252449
J Am Med Dir Assoc. 2017 Jul 1;18(7):636.e7-636.e12
pubmed: 28558966
J Neurol Neurosurg Psychiatry. 1988 Jul;51(7):995-7
pubmed: 3204407
Clin Chem Lab Med. 2011 Mar;49(3):385-91
pubmed: 21275816
Neuroepidemiology. 1990;9(1):27-38
pubmed: 2330069
Arch Neurol. 1993 Oct;50(10):1029-39
pubmed: 8215960
Age Ageing. 2017 Sep 1;46(5):729-738
pubmed: 28541374
J Alzheimers Dis. 2017;60(4):1295-1312
pubmed: 29036826
Age Ageing. 1996 Jul;25(4):313-6
pubmed: 8831878
J Geriatr Psychiatry Neurol. 1997 Jul;10(3):93-8
pubmed: 9322130
Am J Alzheimers Dis Other Demen. 2018 Jun;33(4):205-214
pubmed: 29468898
Int Psychogeriatr. 2008 Aug;20(4):840-52
pubmed: 18177542
J Rehabil Med. 2008 Oct;40(9):755-60
pubmed: 18843429
J Geriatr Phys Ther. 2018 Oct/Dec;41(4):194-203
pubmed: 28005829
Gerontology. 2018;64(4):401-412
pubmed: 29268250
Exerc Sport Sci Rev. 2006 Jan;34(1):29-35
pubmed: 16394812
BMC Geriatr. 2016 May 18;16:106
pubmed: 27193287
J Chronic Dis. 1956 May;3(5):459-77
pubmed: 13306753
Mov Disord. 2000 Jan;15(1):24-9
pubmed: 10634238
Syst Rev. 2016 Dec 5;5(1):210
pubmed: 27919275
Schizophr Bull. 2017 Sep 1;43(5):956-971
pubmed: 28911050
Behav Brain Res. 2002 Nov 15;136(2):593-603
pubmed: 12429421
Neurology. 2004 Sep 28;63(6):975-82
pubmed: 15452286
Alzheimer Dis Assoc Disord. 1990 Winter;4(4):217-25
pubmed: 2264979
Int Psychogeriatr. 2012 May;24(5):834-44
pubmed: 22185768
Arch Neurol. 1991 Feb;48(2):148-54
pubmed: 1993005
Alzheimer Dis Assoc Disord. 2019 Jan-Mar;33(1):54-61
pubmed: 30371515