Towards the Identification of Antibiotic-Resistant Bacteria Causing Urinary Tract Infections Using Volatile Organic Compounds Analysis-A Pilot Study.

E. coli antibiotic resistance bacteria gas chromatography-mass spectrometry metabolite profiles susceptibility urinary tract infection volatile

Journal

Antibiotics (Basel, Switzerland)
ISSN: 2079-6382
Titre abrégé: Antibiotics (Basel)
Pays: Switzerland
ID NLM: 101637404

Informations de publication

Date de publication:
11 Nov 2020
Historique:
received: 28 09 2020
revised: 08 11 2020
accepted: 10 11 2020
entrez: 14 11 2020
pubmed: 15 11 2020
medline: 15 11 2020
Statut: epublish

Résumé

Antibiotic resistance is an unprecedented threat to modern medicine. The analysis of volatile organic compounds (VOCs) from bacteria potentially offers a rapid way to determine antibiotic susceptibility in bacteria. This study aimed to find the optimal conditions to obtain the maximum number of VOCs detected which next allowed the assessment of differences in VOC profiles between susceptible and resistant isolates of

Identifiants

pubmed: 33187091
pii: antibiotics9110797
doi: 10.3390/antibiotics9110797
pmc: PMC7697827
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : National Institute for Health Research (NIHR) Research Capability Funding (RCF), Avon Primary Care Research Collaborative
ID : -

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Auteurs

Keith Hewett (K)

Department of Applied Sciences, Faculty of Health and Applied Sciences, University of the West of England, Coldharbour Lane, Bristol BS16 1QY, UK.

Natalia Drabińska (N)

Department of Applied Sciences, Faculty of Health and Applied Sciences, University of the West of England, Coldharbour Lane, Bristol BS16 1QY, UK.
Department of Chemistry and Biodynamics of Food, Institute of Animal Reproduction and Food Research of Polish Academy of Sciences, 10-748 Olsztyn, Poland.

Paul White (P)

Applied Statistics Group, Department of Engineering, Design and Mathematics, Faculty of Environment and Technology, University of the West of England, Bristol BS16 1QY, UK.

Matthew B Avison (MB)

School of Cellular & Molecular Medicine, Faculty of Life Sciences, University of Bristol, Bristol BS8 1TD, UK.

Raj Persad (R)

Bristol Royal Infirmary and Bristol Urological Institute, Southmead Hospital, Bristol BS10 5BN, UK.

Norman Ratcliffe (N)

Department of Applied Sciences, Faculty of Health and Applied Sciences, University of the West of England, Coldharbour Lane, Bristol BS16 1QY, UK.

Ben de Lacy Costello (BL)

Department of Applied Sciences, Faculty of Health and Applied Sciences, University of the West of England, Coldharbour Lane, Bristol BS16 1QY, UK.

Classifications MeSH