Mediterranean Personalized Diet Combined with Physical Activity Therapy for the Prevention of Cardiovascular Diseases in Italian Women.


Journal

Nutrients
ISSN: 2072-6643
Titre abrégé: Nutrients
Pays: Switzerland
ID NLM: 101521595

Informations de publication

Date de publication:
11 Nov 2020
Historique:
received: 20 10 2020
revised: 06 11 2020
accepted: 09 11 2020
entrez: 14 11 2020
pubmed: 15 11 2020
medline: 13 4 2021
Statut: epublish

Résumé

Cardiovascular diseases (CVDs) and inflammatory risk indexes are used to calculate the exposure to morbidity. Most of them are suggested by the American College of Cardiology/American Heart Association to predict the risk of CVDs diagnosis in primary prevention, instead of treating the ongoing pathology. Prevention starts from habit changes with the prescription of diet and physical activity (PA). The aim of the study is to investigate the effectiveness of a personalized Mediterranean Diet (MD) and a PA intervention, on the risk indexes Atherogenic Index of Plasma (AIP), Lipid Accumulation Product (LAP) and Fatty Liver Index (FLI) in a population of women at risk of CVDs with different pathological conditions. After treatment, patients achieved the best results in body composition (BC) and laboratory tests. The BC analysis showed a significant reduction of total body Fat Mass (FM). CVDs risk indexes significantly decreased, except for Neutrophil/Lymphocyte (NLR) and Platelet/Lymphocyte Ratios (PLR). The reduction of the CVDs indexes associated with lipid profile was linked to both weight and FM decrease. AIP and LAP were significantly reduced when losing fat mass and body weight, respectively. A personalized MD therapy plus a PA program led to body weight loss, BC remodelling and risk indexes reduction.

Identifiants

pubmed: 33187188
pii: nu12113456
doi: 10.3390/nu12113456
pmc: PMC7697155
pii:
doi:

Substances chimiques

Lipids 0

Types de publication

Journal Article Observational Study

Langues

eng

Sous-ensembles de citation

IM

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Auteurs

Laura Di Renzo (L)

Section of Clinical Nutrition and Nutrigenomic, Department of Biomedicine and Prevention, University of Rome Tor Vergata, 00133 Rome, Italy.
Department of Biomedicine and Prevention, University of Rome Tor Vergata, 00133 Rome, Italy.

Giulia Cinelli (G)

School of Specialization in Food Sciences, University of Rome Tor Vergata, 00133 Rome, Italy.
Predictive and Preventive Medicine Research Unit, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.

Maria Dri (M)

Department of Surgical Sciences, School of Applied Medical-Surgical Sciences, University of Rome Tor Vergata, 00133 Rome, Italy.

Paola Gualtieri (P)

Section of Clinical Nutrition and Nutrigenomic, Department of Biomedicine and Prevention, University of Rome Tor Vergata, 00133 Rome, Italy.

Alda Attinà (A)

School of Specialization in Food Sciences, University of Rome Tor Vergata, 00133 Rome, Italy.

Claudia Leggeri (C)

School of Specialization in Food Sciences, University of Rome Tor Vergata, 00133 Rome, Italy.

Giuseppe Cenname (G)

Comando Generale Arma Carabinieri, Direzione di Sanità, 00197 Rome, Italy.

Ernesto Esposito (E)

Department of Human Policies (General Directorate) of Basilicata Region, 85100 Potenza, Italy.

Alberto Pujia (A)

Department of Biomedicine and Prevention, University of Rome Tor Vergata, 00133 Rome, Italy.

Gaetano Chiricolo (G)

Department of Biomedicine and Prevention, University of Rome Tor Vergata, 00133 Rome, Italy.

Chiara Salimei (C)

Department of Systems Medicine, University of Rome Tor Vergata, 00133 Rome, Italy.

Antonino De Lorenzo (A)

Section of Clinical Nutrition and Nutrigenomic, Department of Biomedicine and Prevention, University of Rome Tor Vergata, 00133 Rome, Italy.

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