Design and impact evaluation of a digital reproductive health program in Rwanda using a cluster randomized design: study protocol.

Adolescent sexual and reproductive health Cluster randomized controlled trial Digital health Family planning and reproductive health Human-centered design Hybrid type 2 effectiveness-implementation study Rwanda Uptake of modern contraceptive methods

Journal

BMC public health
ISSN: 1471-2458
Titre abrégé: BMC Public Health
Pays: England
ID NLM: 100968562

Informations de publication

Date de publication:
13 Nov 2020
Historique:
received: 11 06 2020
accepted: 21 10 2020
entrez: 14 11 2020
pubmed: 15 11 2020
medline: 15 5 2021
Statut: epublish

Résumé

Rwandan adolescents have limited access to high-quality family planning and reproductive health (FP/RH) information and care to prevent unplanned pregnancy and HIV/STIs. In addition to the immediate implications for health and well-being, teenage pregnancy is a significant cause of school drop-out, limiting girls' future potential and employment opportunities. This study introduces a direct-to-consumer digital education program that uses storytelling to deliver age-appropriate FP/RH information and economic empowerment training to adolescents. It also facilitates access to high-quality, youth-friendly FP/RH care and products. We evaluate two different school-based models of its implementation to understand how to optimize the uptake of contraception and HIV testing among adolescents. The study consists of two distinct phases. The first formative intervention design phase, conducted from 2016 to 2019, used a human-centered design methodology to develop the intervention alongside over 600 Rwandan adolescents, their parents, teachers, and healthcare providers. Through this methodology, we sought to maximize the fit between evidence-based practices (uptake of modern contraception and HIV testing) and the implementation context of adolescents in Rwanda. The second phase is an impact evaluation, in which we will use a Hybrid Trial Type 2 Effectiveness-Implementation study design to determine the overall effectiveness of this digital intervention as well as the relative effectiveness of the two different school-based implementation models. This takes the form of a 3-arm cluster-randomized non-inferiority trial, with a sample of 6000 youth aged 12-19 in 60 schools across 8 districts in Rwanda. Primary outcome measures include use of modern contraception, delayed initiation of childbearing, and uptake of HIV testing. This study will yield insights into not only whether this digital intervention is successful in achieving the intended sexual and reproductive health outcomes, but also which mechanisms are likely to drive this effectiveness. The methodologies used are broadly applicable to the design, implementation, and evaluation of other behavior-based health programs in low and middle-income countries. ClinicalTrials.gov Identifier: NCT04198272 . Prospectively registered 13 December 2019.

Sections du résumé

BACKGROUND BACKGROUND
Rwandan adolescents have limited access to high-quality family planning and reproductive health (FP/RH) information and care to prevent unplanned pregnancy and HIV/STIs. In addition to the immediate implications for health and well-being, teenage pregnancy is a significant cause of school drop-out, limiting girls' future potential and employment opportunities. This study introduces a direct-to-consumer digital education program that uses storytelling to deliver age-appropriate FP/RH information and economic empowerment training to adolescents. It also facilitates access to high-quality, youth-friendly FP/RH care and products. We evaluate two different school-based models of its implementation to understand how to optimize the uptake of contraception and HIV testing among adolescents.
METHODS METHODS
The study consists of two distinct phases. The first formative intervention design phase, conducted from 2016 to 2019, used a human-centered design methodology to develop the intervention alongside over 600 Rwandan adolescents, their parents, teachers, and healthcare providers. Through this methodology, we sought to maximize the fit between evidence-based practices (uptake of modern contraception and HIV testing) and the implementation context of adolescents in Rwanda. The second phase is an impact evaluation, in which we will use a Hybrid Trial Type 2 Effectiveness-Implementation study design to determine the overall effectiveness of this digital intervention as well as the relative effectiveness of the two different school-based implementation models. This takes the form of a 3-arm cluster-randomized non-inferiority trial, with a sample of 6000 youth aged 12-19 in 60 schools across 8 districts in Rwanda. Primary outcome measures include use of modern contraception, delayed initiation of childbearing, and uptake of HIV testing.
DISCUSSION CONCLUSIONS
This study will yield insights into not only whether this digital intervention is successful in achieving the intended sexual and reproductive health outcomes, but also which mechanisms are likely to drive this effectiveness. The methodologies used are broadly applicable to the design, implementation, and evaluation of other behavior-based health programs in low and middle-income countries.
TRIAL REGISTRATION BACKGROUND
ClinicalTrials.gov Identifier: NCT04198272 . Prospectively registered 13 December 2019.

Identifiants

pubmed: 33187485
doi: 10.1186/s12889-020-09746-7
pii: 10.1186/s12889-020-09746-7
pmc: PMC7662730
doi:

Banques de données

ClinicalTrials.gov
['NCT04198272']

Types de publication

Clinical Trial Protocol Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1701

Subventions

Organisme : United States Agency for International Development
ID : 7200AA18CA00047
Organisme : David and Lucile Packard Foundation
ID : 2018-68175

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Auteurs

Cara Nolan (C)

School of Public Health, University of California, Berkeley, 2121 Berkeley Way West, MC 7360, Berkeley, CA, 94720, USA. cara_nolan@berkeley.edu.

Laura Packel (L)

School of Public Health, University of California, Berkeley, 2121 Berkeley Way West, MC 7360, Berkeley, CA, 94720, USA.

Rebecca Hope (R)

YLabs, 2nd Floor, Golden Plaza, KG 546 St. Kacyiru, Kigali, Rwanda.

Jordan Levine (J)

YLabs, 2nd Floor, Golden Plaza, KG 546 St. Kacyiru, Kigali, Rwanda.

Laura Baringer (L)

YLabs, 2nd Floor, Golden Plaza, KG 546 St. Kacyiru, Kigali, Rwanda.

Emmyson Gatare (E)

YLabs, 2nd Floor, Golden Plaza, KG 546 St. Kacyiru, Kigali, Rwanda.

Aline Umubyeyi (A)

Department of Epidemiology and Biostatistics, School of Public Health, College of Medicine and Health Sciences, University of Rwanda, P.O. Box: 5229, Kigali, Rwanda.

Felix Sayinzoga (F)

Rwanda Biomedical Center, KG 17 Ave, towards Amahoro Stadium, Remera, Rukiri II, Remera, Gasabo, Kigali, Rwanda.

Michael Mugisha (M)

Department of Epidemiology and Biostatistics, School of Public Health, College of Medicine and Health Sciences, University of Rwanda, P.O. Box: 5229, Kigali, Rwanda.

Janepher Turatsinze (J)

Society for Family Health, Rwanda, Plot 99 KG543 St. Kacyiru, PO Box: 3040, Kigali, Rwanda.

Aimee Naganza (A)

Society for Family Health, Rwanda, Plot 99 KG543 St. Kacyiru, PO Box: 3040, Kigali, Rwanda.

Laiah Idelson (L)

YTH Initiative, ETR, 1630 San Pablo Avenue, Suite 500, Oakland, CA, 94612, USA.

Stefano Bertozzi (S)

School of Public Health, University of California, Berkeley, 2121 Berkeley Way West, MC 7360, Berkeley, CA, 94720, USA.

Sandra McCoy (S)

School of Public Health, University of California, Berkeley, 2121 Berkeley Way West, MC 7360, Berkeley, CA, 94720, USA.

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Classifications MeSH