T1 Mapping Quantifies Spinal Cord Compression in Patients With Various Degrees of Cervical Spinal Canal Stenosis.
MRI
T1 mapping
T1 relaxometry
cervical spinal canal stenosis
cervical spondylotic myelopathy
spinal cord compression
Journal
Frontiers in neurology
ISSN: 1664-2295
Titre abrégé: Front Neurol
Pays: Switzerland
ID NLM: 101546899
Informations de publication
Date de publication:
2020
2020
Historique:
received:
20
06
2020
accepted:
09
10
2020
entrez:
16
11
2020
pubmed:
17
11
2020
medline:
17
11
2020
Statut:
epublish
Résumé
Age-related degeneration of the cervical spinal column is the most common cause of spinal cord lesions. T1 mapping has been shown to indicate the grade and site of spinal cord compression in low grade spinal canal stenosis (SCS). Aim of our study was to further investigate the diagnostic potential of a novel T1 mapping method at 0.75 mm resolution and 4 s acquisition time in 31 patients with various grades of degenerative cervical SCS. T1 mapping was performed in axial sections of the stenosis as well as above and below. Included subjects received standard T2-weighted MRI of the cervical spine (including SCS-grading 0-III), electrophysiological, and clinical examination. We found that patients with cervical SCS showed a significant difference in T1 relaxation times within the stenosis (727 ± 66 ms, mean ± standard deviation) in comparison to non-stenotic segments above (854 ± 104 ms,
Identifiants
pubmed: 33193022
doi: 10.3389/fneur.2020.574604
pmc: PMC7662110
doi:
Types de publication
Journal Article
Langues
eng
Pagination
574604Informations de copyright
Copyright © 2020 Maier, Hofer, Eggert, Schregel, Psychogios, Frahm, Bähr and Liman.
Références
Global Spine J. 2017 Sep;7(6):572-586
pubmed: 28894688
NMR Biomed. 2019 Nov;32(11):e4142
pubmed: 31393649
Spine (Phila Pa 1976). 1990 Nov;15(11):1148-52
pubmed: 2267609
AJR Am J Roentgenol. 2011 Jul;197(1):W134-40
pubmed: 21700974
Neuroimage Clin. 2019;21:101639
pubmed: 30553763
Nervenarzt. 2018 Jun;89(6):620-631
pubmed: 29663022
J Bone Joint Surg Br. 1998 Jan;80(1):19-24
pubmed: 9460946
Global Spine J. 2018 Aug;8(5):527-534
pubmed: 30258760
Neurosurgery. 2018 Oct 1;83(4):810-818
pubmed: 29165642
Magn Reson Med. 2018 Apr;79(4):2142-2148
pubmed: 28736946
Spine (Phila Pa 1976). 2019 Jan 1;44(1):E26-E32
pubmed: 29952883
Dtsch Arztebl Int. 2008 May;105(20):366-72
pubmed: 19626174
Spine (Phila Pa 1976). 2000 Mar 15;25(6):670-6
pubmed: 10752097
Magn Reson Med. 2016 Mar;75(3):1341-5
pubmed: 25920491
Nat Methods. 2012 Jun 28;9(7):676-82
pubmed: 22743772
J Bone Joint Surg Br. 1987 Mar;69(2):215-9
pubmed: 3818752
Spine J. 2003 Jan-Feb;3(1):68-81
pubmed: 14589250
Evid Based Spine Care J. 2010 Aug;1(2):56-7
pubmed: 23637669
Magn Reson Med. 2016 May;75(5):2094-9
pubmed: 26094973
Medicine (Baltimore). 2017 Jul;96(30):e7623
pubmed: 28746221
Spine (Phila Pa 1976). 2002 Oct 15;27(20):2205-10; discussion 2210-1
pubmed: 12394893
Br J Neurosurg. 2018 Dec;32(6):595-598
pubmed: 29688066
Magn Reson Med. 2008 Jul;60(1):213-9
pubmed: 18581383