Bacterial Spore mRNA - What's Up With That?

Bacillus germination mRNA spores sporulation

Journal

Frontiers in microbiology
ISSN: 1664-302X
Titre abrégé: Front Microbiol
Pays: Switzerland
ID NLM: 101548977

Informations de publication

Date de publication:
2020
Historique:
received: 18 08 2020
accepted: 28 09 2020
entrez: 16 11 2020
pubmed: 17 11 2020
medline: 17 11 2020
Statut: epublish

Résumé

Bacteria belonging to the orders Bacillales and Clostridiales form spores in response to nutrient starvation. From a simplified morphological perspective, the spore can be considered as comprising a central protoplast or core, that is, enveloped sequentially by an inner membrane (IM), a peptidoglycan cortex, an outer membrane, and a proteinaceous coat. All of these structures are characterized by unique morphological and/or structural features, which collectively confer metabolic dormancy and properties of environmental resistance to the quiescent spore. These properties are maintained until the spore is stimulated to germinate, outgrow and form a new vegetative cell. Spore germination comprises a series of partially overlapping biochemical and biophysical events - efflux of ions from the core, rehydration and IM reorganization, disassembly of cortex and coat - all of which appear to take place in the absence of

Identifiants

pubmed: 33193276
doi: 10.3389/fmicb.2020.596092
pmc: PMC7649253
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

596092

Informations de copyright

Copyright © 2020 Setlow and Christie.

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Auteurs

Peter Setlow (P)

Department of Molecular Biology and Biophysics, UConn Health, Farmington, CT, United States.

Graham Christie (G)

Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, United Kingdom.

Classifications MeSH