Efficacy of Topiramate Alone and Topiramate Plus Vitamin D3 in the Prophylaxis of Pediatric Migraine: A Randomized Clinical Trial.

Child Migraine Prophylaxis Topiramate Vitamin D3

Journal

Iranian journal of child neurology
ISSN: 1735-4668
Titre abrégé: Iran J Child Neurol
Pays: Iran
ID NLM: 101463836

Informations de publication

Date de publication:
2020
Historique:
received: 27 07 2017
accepted: 31 12 2019
entrez: 16 11 2020
pubmed: 17 11 2020
medline: 17 11 2020
Statut: ppublish

Résumé

Topiramate is effective in the prevention of pediatric migraine, and studies show that vitamin D In a single-blinded, randomized, clinical trial, 5-15-year-old children with migraine headaches, referred to the Pediatric Neurology Clinic of Shahid Sadoughi Medical Sciences University, Yazd, Iran from January 2016 to January 2017, were randomly allocated to receive 2 mg/kg/day of topiramate or 2 mg/kg/day of topiramate plus one 500,000 IU vitamin D Totally, 31 female and 26 male children with the mean age of 10.02±2.11 years were evaluated. Both drugs were effective in the reduction of monthly frequency, severity, duration, and disability for headaches. Nevertheless, the combination of topiramate and vitamin D A combination of topiramate and vitamin D

Identifiants

pubmed: 33193786
pii: ijcn-14-077
pmc: PMC7660031

Types de publication

Journal Article

Langues

eng

Pagination

77-86

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Auteurs

Razieh Fallah (R)

Department of Pediatrics, Growth Disorders of Children Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.

Saeedreza Sarraf Yazd (S)

Department of Clinical Pharmacology, Faculty of Pharmacy, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.

Seid Mojtaba Sohrevardi (SM)

Department of Clinical Pharmacology, Faculty of Pharmacy, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.

Classifications MeSH