Cushing´s syndrome: high aggressiveness of low-grade tumors.
Cushing’s syndrome
cortisol
endogenous
exogenous
exposition
supraphysiological
Journal
The Pan African medical journal
ISSN: 1937-8688
Titre abrégé: Pan Afr Med J
Pays: Uganda
ID NLM: 101517926
Informations de publication
Date de publication:
2020
2020
Historique:
received:
31
05
2020
accepted:
02
07
2020
entrez:
16
11
2020
pubmed:
17
11
2020
medline:
15
1
2021
Statut:
epublish
Résumé
Cushing´s syndrome is caused by prolonged exposition supraphysiological to endogenous or exogenous cortisol. Ectopic production of adrenocorticotropic hormone by lung carcinoid tumors is relatively rare. Most documented cases have been reported individually. This rare neoplasm low grade that may secrete adrenocorticotropin (ACTH) leading to rapid development of hypercortisolism which is the main mode of discovery, can be a real aggressive form. This report shows a high aggressiveness of this endocrine neoplasia, wich was marked on the general, morphological, bone and psychiatric level. The trivialization of clinical signs had caused the delay in diagnosis with irreparable bone consequences.
Identifiants
pubmed: 33193969
doi: 10.11604/pamj.2020.36.315.23901
pii: PAMJ-36-315
pmc: PMC7603813
doi:
Substances chimiques
Adrenocorticotropic Hormone
9002-60-2
Hydrocortisone
WI4X0X7BPJ
Types de publication
Case Reports
Langues
eng
Sous-ensembles de citation
IM
Pagination
315Informations de copyright
Copyright: Faycal El Guendouz et al.
Déclaration de conflit d'intérêts
The authors declare no competing of interests.
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